Correlative Imaging with Multi-energy X-ray Tomography

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: Dr. Ford’s research lab has built upon a strong background in preclinical micro-computed tomography (micro-CT) imaging of the lung to develop multi-energy contrast-enhanced micro-CT imaging protocols using iodine and xenon as contrast agents to visualize the blood vessels and airways respectively. We have also developed new imaging techniques on the biomedical beam line (BMIT) of the Canadian Light Source Synchrotron facility (CLS), including the first K-edge subtraction (KES) imaging of xenon and the first images using the respiratory signal from the rodent to trigger image acquisition during a specified respiratory phase. Our techniques for micro-CT and on the BMIT beam line will enable