Telemetry implant system to collect and analyze physiological data on free-moving animals

遥测植入系统，用于收集和分析自由移动动物的生理数据

• 批准号: RTI-2018-00567
• 负责人: Cant, John
• 金额: $ 10.84万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642194
• 关键词: Telemetry; implant; system; collect; analyze

The applicants conduct research to improve the health and welfare of animals under human care, reduce costs of production of foods of animal origin, increase the value of animal products, and reduce waste outputs and the environmental footprint of livestock production. A new interdisciplinary initiative among animal biology researchers at the University of Guelph is related to precision livestock management, where large volumes of data collected automatically, continuously and remotely on individual animals and their environment are used to make software-supported decisions on individual management interventions like timing and amount of feed delivery, lighting schedule, ventilation rate, segregation patterns in a barn, etc. The requested equipment is a telemetry implant system that automatically and continuously collects, and wirelessly transmits to a computer, data on body temperature, blood pressure, heart rate, motor neuron activity, and interstitial glucose concentration from up to 16 animals simultaneously. The hands-off approach to sensing of internal state allows physiology of free-moving, conscious animals to be monitored without inducing stress typical of sampling procedures involving restraint or needle puncture. This feature is particularly useful for studying fear and panic responses, which is necessary to improve animal welfare. Stress responses during sampling may also confound assessments of physiological state, which is a concern when evaluating the quality of various nutritional or environmental interventions. Further, the ability to collect time course data with telemetry implants is valuable because of the increased density of information compared to a single measure. The requested equipment will contribute to training and research activities of 12 graduate students (10 MSc + 8 PhD) and 3 PDF now, and 17 graduate students and numerous undergraduates over the coming 5 years. The rapidly growing use of biosensors in agriculture is generating a need for HQP familiar with the equipment and its exploitation.

申请人开展研究，以改善人类护理下动物的健康和福利，降低动物源性食品的生产成本，增加动物产品的价值，减少废物产出和畜牧业生产的环境足迹。圭尔夫大学动物生物学研究人员之间的一项新的跨学科倡议与精确牲畜管理有关，其中自动，连续和远程收集的关于个体动物及其环境的大量数据用于对个体管理干预做出软件支持的决策，如饲料输送的时间和数量，照明时间表，通风率，谷仓中的隔离模式，所要求的设备是遥测植入系统，该系统可同时自动连续收集多达16只动物的体温、血压、心率、运动神经元活动和间质葡萄糖浓度数据，并将其无线传输至计算机。感测内部状态的不干涉方法允许监测自由移动的有意识动物的生理学，而不会引起涉及约束或针刺的采样程序的典型应力。这一特征对于研究恐惧和恐慌反应特别有用，这对于改善动物福利是必要的。采样期间的应激反应也可能混淆对生理状态的评估，这是评估各种营养或环境干预措施质量时的一个问题。此外，由于与单一测量相比，信息密度增加，因此使用遥测植入物收集时程数据的能力是有价值的。所要求的设备将有助于12名研究生（10名硕士+8名博士）和3名PDF的培训和研究活动，以及未来5年内的17名研究生和许多本科生。生物传感器在农业中的快速增长的使用产生了对熟悉设备及其开发的HQP的需求。