Enabling quantitative research in nanotechnology with a NanoSight NS300 Particle Characterization Analyzer.

使用 NanoSight NS300 颗粒表征分析仪实现纳米技术的定量研究。

• 批准号: RTI-2018-01028
• 负责人: Guay, Daniel
• 金额: $ 10.93万
• 依托单位: Institut national de la recherche scientifique
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642336
• 关键词: Enabling; quantitative; research; nanotechnology; NanoSight

Nanotechnology offers many promising solutions for technologies of the future, but also raises concerns about potential health and environmental impacts. Considering the global importance of this field, an unprecedented research initiative is currently underway to identify new properties for nanomaterials, tune functionality, and better understand nanomaterial-biomolecular interactions. Because the properties of nanomaterials are typically mediated by their outer surface that interfaces with the external environment, their surface chemistry, size, surface area, and hence the absolute concentration of nanoparticles are expected to directly impact performance. Unfortunately, available data does not consistently relate performance (etc.) to size or absolute nanoparticle concentration. As such, it is difficult to draw meaningful conclusions regarding performance/’toxicity’ within a given class of nanomaterial or across different classes. Such an understanding would not only pave the way for better framing potential biological concerns (therapeutic/environmental applications) but also leads to new opportunities for synergy between nanomaterials and chemical/physical processes.

纳米技术为未来的技术提供了许多有前途的解决方案，但也引起了对潜在健康和环境影响的担忧。考虑到这一领域的全球重要性，目前正在进行一项前所未有的研究计划，以确定纳米材料的新特性，调整功能，并更好地了解纳米材料-生物分子相互作用。由于纳米材料的性质通常由其与外部环境接触的外表面介导，因此其表面化学、尺寸、表面积以及纳米颗粒的绝对浓度预计将直接影响性能。不幸的是，现有数据并不总是与性能（等）相关。尺寸或绝对纳米颗粒浓度。因此，很难在给定类别的纳米材料或不同类别的纳米材料中得出有关性能/“毒性”的有意义的结论。这种理解不仅为更好地构建潜在的生物学问题（治疗/环境应用）铺平了道路，而且还为纳米材料与化学/物理过程之间的协同增效带来了新的机会。