Development of breathalyzer biosensor for cannabis detection**

开发用于大麻检测的呼吸分析仪生物传感器**

基本信息

  • 批准号:
    537838-2018
  • 负责人:
  • 金额:
    $ 1.82万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Engage Grants Program
  • 财政年份:
    2018
  • 资助国家:
    加拿大
  • 起止时间:
    2018-01-01 至 2019-12-31
  • 项目状态:
    已结题

项目摘要

Biosensors are analytical devices which consist of biological molecules attached to the sensor surface that bind specifically to target analyte molecules; upon binding a biochemical signal then converted to an electric signal by a transducer producing simple signal readout, such as "Yes", or "No". Biosensor development combines advanced nanotechnologies with the fundamentals of biological recognition with the purpose of developing new sensors and devices for drug testing, food safety and environmental control.**The main goal of this project is to establish collaboration between SannTek Labs and Dr. Leonenko's laboratory at University of Waterloo with the purpose to identify the most optimal biosensing protocols for the development of breathalyzer sensor device for cannabis, which will allow for the quick and simple testing of the air (breath) in order to identify the presence of cannabis.**Dr. Leonenko's laboratory has expertise in biophysics, nanotechnology and leads NSERC-funded research program in biosensor development. SannTek Labs is a rapidly growing high-performance startup company, based out of the Velocity entrepreneurship program at the University of Waterloo, and has a goal of building and bringing to market its first innovative product, a breathalyzer device for cannabis detection.**The complementary expertise and efforts of both groups will be combined to achieve the successful development of the SannTek cannabis breathalyzer, and the protocols obtained within this project will be immediately incorporated into the sensor development for production. **The device for cannabis testing is a desperately needed product within Canada. This sensor device will significantly help and improve the drug testing procedures, and thus it will contribute to the safety of all Canadians by helping keep drug-impaired individuals off the roads and away from dangerous activities.**
生物传感器是由附着于传感器表面的生物分子组成的分析装置,其特异性结合目标分析物分子;在结合时,生物化学信号然后通过换能器转换为电信号,产生简单的信号读出,例如“是”或“否”。生物传感器的发展结合了先进的纳米技术与生物识别的基本原理,目的是开发新的传感器和设备,用于药物测试,食品安全和环境控制。该项目的主要目标是在SannTek Labs和滑铁卢大学Leonenko博士的实验室之间建立合作,目的是确定用于开发大麻呼吸测醉传感器设备的最佳生物传感协议,这将允许快速简单地测试空气(呼吸)以识别大麻的存在。Leonenko博士的实验室拥有生物物理学、纳米技术方面的专业知识,并领导了NSERC资助的生物传感器开发研究项目。SannTek Labs是一家快速发展的高性能创业公司,总部位于滑铁卢大学的Velocity创业计划,目标是建立并将其第一个创新产品推向市场,即用于大麻检测的呼气测醉器设备。两个小组的互补专业知识和努力将结合起来,以实现SannTek大麻呼气测醉器的成功开发,该项目中获得的协议将立即纳入传感器的生产开发。** 大麻测试设备是加拿大迫切需要的产品。这种传感器设备将大大有助于和改善药物测试程序,因此它将有助于所有加拿大人的安全,帮助吸毒者远离道路和危险活动。

项目成果

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Leonenko, Zoya其他文献

Nanoscale Electrostatic Domains in Cholesterol-Laden Lipid Membranes Create a Target for Amyloid Binding
  • DOI:
    10.1016/j.bpj.2012.06.053
  • 发表时间:
    2012-08-22
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
    Drolle, Elizabeth;Gaikwad, Ravi M.;Leonenko, Zoya
  • 通讯作者:
    Leonenko, Zoya
Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy
  • DOI:
    10.1016/j.bios.2013.10.060
  • 发表时间:
    2014-04-15
  • 期刊:
  • 影响因子:
    12.6
  • 作者:
    Hane, Francis T.;Lee, Brenda Y.;Leonenko, Zoya
  • 通讯作者:
    Leonenko, Zoya
Adhesive interaction measured between AFM probe and lung epithelial type II cells
  • DOI:
    10.1016/j.ultramic.2007.02.036
  • 发表时间:
    2007-10-01
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    Leonenko, Zoya;Finot, Eric;Amrein, Matthias
  • 通讯作者:
    Amrein, Matthias
An elevated level of cholesterol impairs self-assembly of pulmonary surfactant into a functional film
  • DOI:
    10.1529/biophysj.107.106310
  • 发表时间:
    2007-07-01
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
    Leonenko, Zoya;Gill, Simardeep;Amrein, Matthias
  • 通讯作者:
    Amrein, Matthias
Kelvin probe force microscopy in application to biomolecular films: Frequency modulation, amplitude modulation, and lift mode
  • DOI:
    10.1016/j.ultramic.2010.02.036
  • 发表时间:
    2010-05-01
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    Moores, Brad;Hane, Francis;Leonenko, Zoya
  • 通讯作者:
    Leonenko, Zoya

Leonenko, Zoya的其他文献

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{{ truncateString('Leonenko, Zoya', 18)}}的其他基金

Langmuir Blodgett Micro Trough for membrane biophysics and nanotechnology research
Langmuir Blodgett 微槽用于膜生物物理学和纳米技术研究
  • 批准号:
    RTI-2023-00463
  • 财政年份:
    2022
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Research Tools and Instruments
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    RGPIN-2017-05030
  • 财政年份:
    2021
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    RGPIN-2017-05030
  • 财政年份:
    2020
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    RGPIN-2017-05030
  • 财政年份:
    2019
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    DGDND-2017-00079
  • 财政年份:
    2019
  • 资助金额:
    $ 1.82万
  • 项目类别:
    DND/NSERC Discovery Grant Supplement
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    RGPIN-2017-05030
  • 财政年份:
    2018
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    DGDND-2017-00079
  • 财政年份:
    2018
  • 资助金额:
    $ 1.82万
  • 项目类别:
    DND/NSERC Discovery Grant Supplement
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    RGPIN-2017-05030
  • 财政年份:
    2017
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Characterization of Antigen-Adjuvant interactions by Atomic Force Microscopy
通过原子力显微镜表征抗原-佐剂相互作用
  • 批准号:
    507593-2017
  • 财政年份:
    2017
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Engage Grants Program
Nanoscale structure of lipid membrane and its role in membrane-mediated interactions
脂质膜的纳米结构及其在膜介导的相互作用中的作用
  • 批准号:
    DGDND-2017-00079
  • 财政年份:
    2017
  • 资助金额:
    $ 1.82万
  • 项目类别:
    DND/NSERC Discovery Grant Supplement

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动机访谈和行为夫妻治疗相结合的干预措施,以减少印度南部的亲密伴侣暴力和酗酒
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改进临床医生和研究人员用于远程监测酒精使用情况的远程呼吸分析仪程序
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基于纳米抗体的电化学生物传感器,用于实时检测气溶胶 SARS-CoV2
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