Utilisation de bactériocines de synthèse pour prévenir les infections alimentaires et vétérinaires

即使在2019年，微生物食品污染也是频繁的(加拿大在2019年1月至2月期间召回了12起微生物产品)。最近发生的罗马沙拉产品污染事件成为加拿大各地的头条新闻。对于食品加工商来说，召回这些产品的成本非常高，但由于消费者对产品失去信心，也损失了收入。2008年爆发的枫叶李斯特氏菌仍然铭刻在加拿大消费者的脑海中。对于食品加工商来说，这类事件严重损害了消费者的利益。传统的化学防腐剂(盐、硝酸盐、亚硫酸盐等)是不够的，不能满足消费者的需求，相反，消费者想要从饮食中去除这些防腐剂，这使得对天然防腐剂的需求不断增长。这种对替代品的需求并不是食品加工商独有的，它影响到食物链中的所有参与者，从畜牧业者到消费者的盘子。因此，必须找到一种解决方案来减少这些微生物污染的发生率，同时满足消费者对天然产品的需求。建议的解决方案是使用细菌素，即由益生菌产生的小的天然抗菌蛋白质，以控制其环境中的病原体。这项技术使我们有可能准确和高效地瞄准我们消费链中发现的病原体。此外，它们是天然的，被加拿大卫生部认可为安全的。这项技术代表了农场动物中化学防腐剂和抗生素的一种真正的天然替代品。

Even in 2019, microbiological food contamination is frequent (12 microbiological recalls between January andFebruary 2019 in Canada). Recent cases of contaminations of Roman salad products have made headlinesacross Canada. These are very expensive for food processors to recall these products, but also lost revenue dueto the loss of consumer confidence in the product. The Maple Leaf outbreak of Listeria in 2008 is still etched inthe minds of Canadian consumers. For the food processor, this type of incident seriously damages thereputation.Traditional chemical preservatives (salts, nitrates, sulphites and others) are insufficient and do not respond tothe consumer's demand, who, on the contrary, wants to remove them from his diet, which allows the demandfor natural preservatives to be in continual growth. This need for alternatives is not unique to food processors,but affects all players in the food chain, from the livestock farmer to the consumer's plate. A solution musttherefore be found to reduce the incidence of these microbiological contaminations, while meeting consumerdemand for natural products.The proposed solution is the use of bacteriocins, that is small, natural antimicrobial proteins produced byprobiotics, to control pathogens in their environment. This technology makes it possible to target precisely andwith high efficiency the pathogens found in our consumption chain. In addition, they are natural and recognizedas safe by Health Canada. This technology represents a real natural alternative to chemical preservatives andantibiotics in farm animals.