Understanding how oxidative stress influences tumor evolution via metabolic reprogramming
了解氧化应激如何通过代谢重编程影响肿瘤进化
基本信息
- 批准号:408069
- 负责人:
- 金额:$ 71.06万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2019
- 资助国家:加拿大
- 起止时间:2019-09-01 至 2024-09-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Although several breast cancers are responsive to targeted therapies and/or chemotherapy, even today, a significant number of women will either never respond to these therapies or unfortunately experience relapse. A significant barrier to long term survi
尽管一些乳腺癌对靶向治疗和/或化疗有反应,但即使在今天,仍有相当多的女性对这些治疗没有反应,或者不幸复发。 长期生存的重大障碍
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Ursini-Siegel Giuseppina其他文献
Ursini-Siegel Giuseppina的其他文献
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{{ truncateString('Ursini-Siegel Giuseppina', 18)}}的其他基金
Inducing oxidative stress as a mechanism to increase the clinical impact of complex I inhibitors in treating aggressive breast cancers.
诱导氧化应激作为增加复合物 I 抑制剂治疗侵袭性乳腺癌临床影响的机制。
- 批准号:
455845 - 财政年份:2021
- 资助金额:
$ 71.06万 - 项目类别:
Operating Grants
Capitalizing on an oxidative stress response to sensitize poor outcome cancers to PARP inhibitors
利用氧化应激反应使预后不良的癌症对 PARP 抑制剂敏感
- 批准号:
408071 - 财政年份:2019
- 资助金额:
$ 71.06万 - 项目类别:
Operating Grants
Defining the mechanisms and therapeutic potential of ShcA-mediated angiogenesis and metabolism that fuel breast tumorigenesis
定义促进乳腺肿瘤发生的 ShcA 介导的血管生成和代谢的机制和治疗潜力
- 批准号:
321218 - 财政年份:2015
- 资助金额:
$ 71.06万 - 项目类别:
Operating Grants
Defining the Molecular Mechanisms and Clinical Implications of p66ShcA as a Driver of the Epithelial to Mesenchymal Transition in Breast Cancer
定义 p66ShcA 作为乳腺癌上皮间质转化驱动因素的分子机制和临床意义
- 批准号:
291181 - 财政年份:2013
- 资助金额:
$ 71.06万 - 项目类别:
Operating Grants
Mechanisms through which ShcA integrates tyrosine kinase signaling to promote breast cancer progression
ShcA 整合酪氨酸激酶信号传导促进乳腺癌进展的机制
- 批准号:
209922 - 财政年份:2010
- 资助金额:
$ 71.06万 - 项目类别:
Operating Grants
Mechanisms through which ShcA integrates tyrosine kinase signaling to promote breast cancer progression.
ShcA 整合酪氨酸激酶信号传导促进乳腺癌进展的机制。
- 批准号:
213334 - 财政年份:2010
- 资助金额:
$ 71.06万 - 项目类别:
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