Understanding how oxidative stress influences tumor evolution via metabolic reprogramming
Understanding how oxidative stress influences tumor evolution via metabolic reprogramming
批准号:
408069
负责人:
Ursini-Siegel Giuseppina
金额:
$71.06万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Although several breast cancers are responsive to targeted therapies and/or chemotherapy, even today, a significant number of women will either never respond to these therapies or unfortunately experience relapse. A significant barrier to long term survi
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Inducing oxidative stress as a mechanism to increase the clinical impact of complex I inhibitors in treating aggressive breast cancers.
-
批准号:455845
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2021
-
负责人:Ursini-Siegel Giuseppina
-
依托单位:
Capitalizing on an oxidative stress response to sensitize poor outcome cancers to PARP inhibitors
-
批准号:408071
-
项目类别:Operating Grants
-
资助金额:$69.11万
-
财政年份:2019
-
负责人:Ursini-Siegel Giuseppina
-
依托单位:
Defining the mechanisms and therapeutic potential of ShcA-mediated angiogenesis and metabolism that fuel breast tumorigenesis
-
批准号:321218
-
项目类别:Operating Grants
-
资助金额:$59.57万
-
财政年份:2015
-
负责人:Ursini-Siegel Giuseppina
-
依托单位:
Defining the Molecular Mechanisms and Clinical Implications of p66ShcA as a Driver of the Epithelial to Mesenchymal Transition in Breast Cancer
-
批准号:291181
-
项目类别:Operating Grants
-
资助金额:$49.94万
-
财政年份:2013
-
负责人:Ursini-Siegel Giuseppina
-
依托单位:
Mechanisms through which ShcA integrates tyrosine kinase signaling to promote breast cancer progression
-
批准号:209922
-
项目类别:Operating Grants
-
资助金额:$49.64万
-
财政年份:2010
-
负责人:Ursini-Siegel Giuseppina
-
依托单位:
Mechanisms through which ShcA integrates tyrosine kinase signaling to promote breast cancer progression.
-
批准号:213334
-
项目类别:Salary Programs
-
资助金额:$21.86万
-
财政年份:2010
-
负责人:Ursini-Siegel Giuseppina
-
依托单位:
海外基金