Study of plant protein aggregation to yield new functional properties
研究植物蛋白聚集以产生新的功能特性
基本信息
- 批准号:RGPIN-2018-04545
- 负责人:
- 金额:$ 3.42万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2019
- 资助国家:加拿大
- 起止时间:2019-01-01 至 2020-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Plant proteins are increasingly used in food and non-food areas owing to their sustainability, biodegradability and functionality in addition to their high nutritive value. Despite the great interest in plant proteins for creating new foods and biomaterials (e.g. emulsions, foams, gels), the molecular basis of their functionality is still far from clear. The long-term goal of my program is to continuously expand our basic understanding of the structure-function relationships of plant proteins and to apply this knowledge to develop healthier foods and biomaterials. The short-term goal focuses on study of plant protein aggregation to yield new functional properties. Globulin proteins from pulses and oats will be selected as models.******Globulin proteins generally form three types of aggregates with distinct morphologies: fibrils, spherical particles and strands. The use of specific protein aggregates with well characterized structures to create functionality is new and has attracted scientific interests. For example, the elongated morphology allows fibrils to create a space filling network at low volume, making them advantageous thickening and gelling ingredients. Aggregate morphology largely determines its functionality. For optimal functionality the aggregation process needs to be controlled to target specific morphology; this can be done if the aggregation mechanisms are understood. Therefore, specifically in this research, we aim to understand the plant globulin protein aggregation mechanisms in controlling aggregate morphology. We will then study how aggregates of different morphology can be used to create new functionality with emphasis on Pickering emulsions and fibirllar/percolating gels. Subsequently, these emulsions and gels will be converted into natural delivery systems of bioactive molecules to improve their stability and controlled release them in the small intestine for better absorption or health benefits. ******The knowledge gained through this research will represent a transformative tool for the food industry to develop emulsion- and gel-based foods of superior quality, with improved characteristics such as a prolonged shelf-life or better sensory properties. These tools will also enable the industry to tailor bioactive molecules (e.g. -3, lutein, enzymes) into novel functional foods to lower the risk of chronic disease and improve public health. The outcomes will benefit pharmaceutical, personal care and bio-product industries as well, which are also demanding natural and sustainable sources of plant origin. From an agricultural perspective, oat and pulse production represent key and major agricultural sectors in Canada. The proposed research will create new value-added opportunities for oat and pulse proteins and thus can enhance the profitability and sustainability of Canadian producers and processors alike.
植物蛋白由于其可持续性、生物降解性和功能性以及其高营养价值而越来越多地用于食品和非食品领域。尽管人们对植物蛋白用于创造新的食品和生物材料(例如乳液,泡沫,凝胶)非常感兴趣,但其功能的分子基础仍然很不清楚。我的计划的长期目标是不断扩大我们对植物蛋白质的结构-功能关系的基本理解,并将这些知识应用于开发更健康的食品和生物材料。短期目标侧重于研究植物蛋白质聚集以产生新的功能特性。将选择豆类和燕麦中的球蛋白作为模型。**球蛋白通常形成具有不同形态的三种类型的聚集体:原纤维、球形颗粒和股。使用具有良好表征结构的特定蛋白质聚集体来产生功能性是新的,并且已经吸引了科学兴趣。例如,细长形态允许原纤维以低体积产生空间填充网络,使其成为有利的增稠和胶凝成分。聚集体形态在很大程度上决定了其功能。为了获得最佳功能,需要控制聚集过程以靶向特定形态;如果理解聚集机制,则可以做到这一点。因此,具体在本研究中,我们的目的是了解植物球蛋白聚集机制控制聚集形态。然后,我们将研究不同形态的聚集体如何被用来创造新的功能,重点是皮克林乳液和纤维/乳化凝胶。随后,这些乳液和凝胶将被转化为生物活性分子的天然递送系统,以提高其稳定性,并在小肠中控制释放,以更好地吸收或有益于健康。** 通过这项研究获得的知识将代表食品行业的一种变革性工具,用于开发具有上级质量的乳液和凝胶食品,这些食品具有更好的特性,如延长的保质期或更好的感官特性。这些工具还将使该行业能够将生物活性分子(例如-3,叶黄素,酶)定制为新型功能性食品,以降低慢性疾病的风险并改善公众健康。这些成果也将使制药、个人护理和生物制品行业受益,这些行业也需要天然和可持续的植物来源。从农业的角度来看,燕麦和豆类生产代表了加拿大的关键和主要农业部门。拟议的研究将为燕麦和豆类蛋白质创造新的增值机会,从而提高加拿大生产商和加工商的盈利能力和可持续性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Chen, Lingyun其他文献
A latent class analysis of community-based rehabilitation needs among Chinese older adults: a mixed study protocol.
- DOI:
10.3389/fpubh.2023.1301752 - 发表时间:
2023 - 期刊:
- 影响因子:5.2
- 作者:
Xu, Lei;Xue, Caixiu;Yang, Ke;Chen, Lingyun;Chen, Xidong;Xie, Xiaohui;Wang, Jia;Wang, Xueting;Wang, Lianhong - 通讯作者:
Wang, Lianhong
Gingerols synergize with anthocyanins to induce antioxidant activity in vitro.
- DOI:
10.3389/fnut.2023.1229015 - 发表时间:
2023 - 期刊:
- 影响因子:5
- 作者:
Abdurrahim, Amna Emhemed;Mazurak, Vera C.;Chen, Lingyun - 通讯作者:
Chen, Lingyun
The Comparable Microenvironment Shared by Colorectal Adenoma and Carcinoma: An Evidence of Stromal Proteomics.
- DOI:
10.3389/fonc.2022.848782 - 发表时间:
2022 - 期刊:
- 影响因子:4.7
- 作者:
Yan, Keqiang;Bai, Bin;Ren, Yan;Cheng, Benliang;Zhang, Xia;Zhou, Haichao;Liang, Yuting;Chen, Lingyun;Zi, Jin;Yang, Qinghai;Zhao, Qingchuan;Liu, Siqi - 通讯作者:
Liu, Siqi
Simultaneous Determination and Pharmacokinetic Study of Metformin and Rosiglitazone in Human Plasma by HPLC-ESI-MS
- DOI:
10.1093/chrsci/49.2.94 - 发表时间:
2011-02-01 - 期刊:
- 影响因子:1.3
- 作者:
Chen, Lingyun;Zhou, Zhifeng;Ma, Ande - 通讯作者:
Ma, Ande
Antioxidant capacities of fractionated barley hordein hydrolysates in relation to peptide structures
- DOI:
10.1002/mnfr.201200252 - 发表时间:
2013-03-01 - 期刊:
- 影响因子:5.2
- 作者:
Bamdad, Fatemeh;Chen, Lingyun - 通讯作者:
Chen, Lingyun
Chen, Lingyun的其他文献
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{{ truncateString('Chen, Lingyun', 18)}}的其他基金
Study of plant protein aggregation to yield new functional properties
研究植物蛋白聚集以产生新的功能特性
- 批准号:
RGPIN-2018-04545 - 财政年份:2022
- 资助金额:
$ 3.42万 - 项目类别:
Discovery Grants Program - Individual
Plant Protein, Structure Function and Nutraceutical Delivery
植物蛋白、结构功能和营养物质输送
- 批准号:
CRC-2019-00243 - 财政年份:2022
- 资助金额:
$ 3.42万 - 项目类别:
Canada Research Chairs
Plant Protein, Structure Function And Nutraceutical Delivery
植物蛋白、结构功能和营养物质输送
- 批准号:
CRC-2019-00243 - 财政年份:2021
- 资助金额:
$ 3.42万 - 项目类别:
Canada Research Chairs
Study of plant protein aggregation to yield new functional properties
研究植物蛋白聚集以产生新的功能特性
- 批准号:
RGPIN-2018-04545 - 财政年份:2021
- 资助金额:
$ 3.42万 - 项目类别:
Discovery Grants Program - Individual
Plant Protein, Structure Function and Nutraceutical Delivery
植物蛋白、结构功能和营养物质输送
- 批准号:
CRC-2019-00243 - 财政年份:2020
- 资助金额:
$ 3.42万 - 项目类别:
Canada Research Chairs
Study of plant protein aggregation to yield new functional properties
研究植物蛋白聚集以产生新的功能特性
- 批准号:
RGPIN-2018-04545 - 财政年份:2020
- 资助金额:
$ 3.42万 - 项目类别:
Discovery Grants Program - Individual
Plant Protein, Structure Function and Nutraceutical Delivery
植物蛋白、结构功能和营养物质输送
- 批准号:
CRC-2019-00243 - 财政年份:2019
- 资助金额:
$ 3.42万 - 项目类别:
Canada Research Chairs
Plant Protein Chemistry and Technology
植物蛋白化学与技术
- 批准号:
1000230038-2013 - 财政年份:2019
- 资助金额:
$ 3.42万 - 项目类别:
Canada Research Chairs
Plant Protein Chemistry and Technology
植物蛋白化学与技术
- 批准号:
1000230038-2013 - 财政年份:2018
- 资助金额:
$ 3.42万 - 项目类别:
Canada Research Chairs
Value-added applications of pulse proteins for human foods
豆类蛋白在人类食品中的增值应用
- 批准号:
488330-2015 - 财政年份:2018
- 资助金额:
$ 3.42万 - 项目类别:
Collaborative Research and Development Grants
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