Upgrades to Multi-Lab Gas Chromatography System

升级至多实验室气相色谱系统

• 批准号: RTI-2020-00116
• 负责人: Field, Catherine
• 金额: $ 10.01万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=693495
• 关键词: Upgrades; Multi; Lab; Gas; Chromatography

Gas chromatography (GC) is the industry-standard method for measuring fatty acids and other lipids in biological samples. Because fatty acids and lipids are involved in many cellular processes in all living things, proper understanding of these processes requires accurate measurements from experimental samples. GC is the most accurate and cost-effective way of performing these analytical measurements.******We are requesting funding for a major upgrade to our comprehensive, multi-lab GC program. This includes (1) an Agilent 8890 GC System, (2) an Agilent 7693 autosampler, and (3) a Thermo TriPlus 100LS autosampler. These autosamplers will be replacements installed on existing GCs. The Lipidomics Core Facility is highly subsidized by the Faculty of Medicine and Dentistry, the Women and Children's Health Research Institute, and the University of Alberta, and provides affordable lipid analytical services to university researchers across faculties. The requested funding will provide strong support to this initiative, benefitting not only the 3 applicants, but also many other investigators who study lipids. ******The collaborative nature of the applicants' shared GC infrastructure is a unique and highly-functional arrangement that benefits all parties who are directly and indirectly involved. Doubling the throughput of fatty acid analysis in the lab of Dr. Field with this dual-channel GC will lead to improvements in quality and shorter wait times for Core Facility users including Drs. Lehner and Proctor. This in-turn will allow the Facility to further develop and expand the analytical methodology offered. The new 8890 GC will be used by trainees and HQP 24 hours a day, 7 days a week in the lab of Dr. Field, and the repaired GCs will be used daily by researchers from across the University. ******More broadly, gas chromatography is an important and heavily-used technique in academia, government, and industry. In addition to their use in measuring lipids and other basic research applications, GCs are widely used for research and development in the petroleum, alternative energy, foods and flavours, cosmetics, healthcare, pharmaceutical, and environmental industries. Trainees who learn to operate and analyze data from GC instruments gain skills that are incredibly valuable for their future careers. The in-depth knowledge gained by using GCs in a research setting is invaluable in producing highly-qualified personnel (HQP) who progress into productive careers in academia, government, industry, and more.*****

气相色谱法（GC）是测定生物样品中脂肪酸和其他脂类的工业标准方法。由于脂肪酸和脂类参与了所有生物的许多细胞过程，因此正确理解这些过程需要从实验样品中进行精确测量。气相色谱是执行这些分析测量的最准确和最经济有效的方法。******我们正在申请资金用于我们全面的多实验室GC项目的重大升级。这包括(1)Agilent 8890 GC系统，(2)Agilent 7693自动进样器，(3)Thermo TriPlus 100LS自动进样器。这些自动进样器将被替换安装在现有的gc上。脂质组学核心设施由医学和牙科学院、妇女和儿童健康研究所以及阿尔伯塔大学高度资助，并为大学各院系的研究人员提供负担得起的脂质分析服务。所要求的资金将为该计划提供强有力的支持，不仅使3名申请人受益，而且使许多其他研究脂质的研究者受益。******申请人共享的GC基础设施的协作性质是一种独特的高功能安排，可使直接或间接参与的所有各方受益。使用这种双通道气相色谱，将Field博士实验室脂肪酸分析的吞吐量提高一倍，将提高质量，缩短Core Facility用户（包括Dr. Field博士）的等待时间。雷纳和普罗科特。这反过来将使基金能够进一步发展和扩大所提供的分析方法。新的8890气相色谱将在Field博士的实验室每天24小时、每周7天由学员和HQP使用，修复后的气相色谱将每天由整个大学的研究人员使用。******更广泛地说，气相色谱法是学术界，政府和工业中重要且广泛使用的技术。除了用于测量脂质和其他基础研究应用外，gc还广泛用于石油，替代能源，食品和香料，化妆品，医疗保健，制药和环境行业的研究和开发。学习操作和分析气相色谱仪器数据的学员获得的技能对他们未来的职业生涯非常有价值。通过在研究环境中使用GCs获得的深入知识对于培养高素质人才（HQP）是非常宝贵的，这些高素质人才将在学术界、政府、工业等领域进入富有成效的职业生涯。*****