Base Metal Complex-Catalyzed Fluoroalkene Transformations: New Routes to Commercially Valuable Fluorocarbon Compounds

贱金属络合物催化氟烯烃转化：生产具有商业价值的氟碳化合物的新途径

• 批准号: 537773-2018
• 负责人: Baker, Ralph
• 金额: $ 10.39万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=699088
• 关键词: Base; Metal; Complex; Catalyzed; Fluoroalkene

Canada is a significant user of refrigerants for a number of applications within its built environment, including refrigeration for food, recreation (skating and curling rinks), and residential and commercial buildings. Fluoroalkenes have recently been identified as the newest generation of refrigerants, propellants and blowing agents due to their greatly reduced global warming potential vs. currently used hydrofluorocarbons. Typical routes to fluoroalkenes, however, are currently energy intensive and often employ toxic reagents such as heavy metals and hydrogen fluoride. In this project we will build on exciting new base-metal catalyzed routes to fluoroalkenes using a newly constructed integrated gas manifold for producing, purifying and isolating gases on the multigram scale. Using readily tunable nickel and copper complex catalysts, commercially available fluoroalkenes will be converted into a host of new fluorocarbon compounds that can serve as more economically and environmentally friendly alternatives to those currently in use. Our ability to prepare a variety of new fluoroalkenes not readily accessible by current routes will allow our industry partner, Arkema (in Canada since 1957) to test them as refrigerants, propellants and blowing agents, as well as new monomers for high-value fluoropolymers. In addition to advancing our fundamental knowledge of base metal organofluorine chemistry, identification of economical routes to new industrially important fluorocarbon products will also contribute to a reduction in global warming currently attributed to fluorocarbon emissions. Moreover, our co-workers will be trained in an exciting area of organofluorine chemistry that offers new applications in pharma and agrichemicals as well as advanced materials.

加拿大是制冷剂的重要用户，用于其建筑环境中的许多应用，包括食品制冷，娱乐（溜冰和冰壶溜冰场）以及住宅和商业建筑。由于其全球变暖的潜力大大降低了，而当前使用的氢氟化合物大大降低了，因此最近已将氟烷烃确定为最新一代的制冷剂，推进剂和吹剂。然而，通往氟烯烃的典型路线目前是能量密集型的，并且通常采用有毒试剂，例如重金属和氟化氢。在这个项目中，我们将使用新建造的集成气歧管，以在多批量表上产生，净化和隔离气体来建立令人兴奋的新碱金属催化路线。使用易于调节的镍和铜复合催化剂，将转换为可获得的氟烷烃，将其转换为许多新的氟化碳化合物，这些化合物可以作为当前正在使用的氟化合物更经济和环保的替代品。我们准备各种新的Fluoroalkenes不容易被当前路线访问的能力将使我们的行业合作伙伴Arkema （自1957年以来，在加拿大）将其作为制冷剂，推进剂和吹式药物以及高价值荧光聚合物的新单体进行测试。除了促进我们对碱金属有机氟化化学的基本知识外，对新工业重要的氟化合物产品的经济途径的识别还将有助于减少目前归因于氟化合物排放的全球变暖。此外，我们的同事将在令人兴奋的Organofluorine化学领域进行培训，该化学能够在制药和农业化学材料以及高级材料中提供新的应用。