Novel instrumentation and models for biomechanical assessment of engineered protection devices

用于工程保护装置生物力学评估的新型仪器和模型

基本信息

  • 批准号:
    RGPIN-2018-04253
  • 负责人:
  • 金额:
    $ 2.33万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Discovery Grants Program - Individual
  • 财政年份:
    2020
  • 资助国家:
    加拿大
  • 起止时间:
    2020-01-01 至 2021-12-31
  • 项目状态:
    已结题

项目摘要

Head and brain injury affects all sectors of society: everyday civilians; military personnel; law enforcement personnel; and youth, adult, amateur and professional athletes. In civilian settings, head injuries occur through blunt impact in automotive collisions and sport incidents. In military and law enforcement, they can occur from blunt impact, ballistic impacts on helmets, and exposure to blast from explosives. Taken together, head-brain injury leads to societal costs of $Billions as well as long term suffering in the injured individual. Engineers play a vital role in understanding, and indeed in designing engineered protection devices for, head protection devices (i.e. helmets). The ability to protect the head is tested using models that fall into one of two categories. The first is metal-rubber experimental models that rely on measurements of parameters including (but not limited to) acceleration due to impact, or pressure in blast, that to varying degrees of accuracy can estimate protection by quantifying how well the protection device limits these accelerations or pressures. The second is computer models that strive to estimate capacity for protection by estimating the amount of impact or blast energy prevented from affecting the human. Computer models require validation to ensure that their outputs exhibit realism and as of now they are not widely used in standardized certification and assessment of protection devices partially because their validation is ongoing. Experimental models are widespread and used in standardized testing and certification, however they are often criticized as poor models for the human. This latter concern stems from the fact that most are constructed to be mechanically robust and re-usable, and as a result they don't, in many cases, accurately model the response of the relatively frailer human. The proposed program addresses these limitations by developing mechanically realistic experimental models and advanced instrumentation that quantify mitigation in mechanical exposure to impact and blast. To protect against these injuries while attempting to lessen the physical burden of the headgear-wearer, protective headgear is being developed with novel material architectures that strive for light-weight while retaining protective efficacy. Preventing transfer of mechanical impact and blast energy is the central goal behind headgear design, and therefore accurate mechanical models and instrumentation are vital in their assessment.
头部和脑部损伤影响社会各阶层:普通平民;军事人员;执法人员;以及青年、成人、业余和专业运动员。在民用环境中,头部受伤是由于汽车碰撞和运动事故中的钝器撞击造成的。在军事和执法中,它们可能发生在钝器撞击,头盔上的弹道撞击,以及暴露在爆炸物的爆炸中。总的来说,颅脑损伤导致数十亿美元的社会成本以及受伤个体的长期痛苦。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Dennison, Christopher其他文献

Investigating the role of zinc and copper binding motifs of trafficking sites in the cyanobacterium Synechocystis PCC 6803.
  • DOI:
    10.1021/bi400492t
  • 发表时间:
    2013-10-01
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Badarau, Adriana;Basle, Arnaud;Firbank, Susan J.;Dennison, Christopher
  • 通讯作者:
    Dennison, Christopher
Regulation of protein function: Crystal packing interfaces and conformational dimerization
蛋白质功能的调节:晶体堆积界面和构象二聚化
  • DOI:
    10.1021/bi800125h
  • 发表时间:
    2008-06-24
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Crowley, Peter B.;Matias, Pedro M.;Dennison, Christopher
  • 通讯作者:
    Dennison, Christopher
FutA2 is a ferric binding protein from Synechocystis PCC 6803
  • DOI:
    10.1074/jbc.m709907200
  • 发表时间:
    2008-05-02
  • 期刊:
  • 影响因子:
    4.8
  • 作者:
    Badarau, Adriana;Firbank, Susan J.;Dennison, Christopher
  • 通讯作者:
    Dennison, Christopher
The influence of protein folding on the copper affinities of trafficking and target sites
  • DOI:
    10.1039/c2dt32166a
  • 发表时间:
    2013-01-01
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Allen, Stephen;Badarau, Adriana;Dennison, Christopher
  • 通讯作者:
    Dennison, Christopher
Important Structural Features of Thiolate-Rich Four-Helix Bundles for Cu(I) Uptake and Removal.
  • DOI:
    10.1021/acs.inorgchem.2c04490
  • 发表时间:
    2023-05-01
  • 期刊:
  • 影响因子:
    4.6
  • 作者:
    Lee, Jaeick;Dalton, Rosemary A.;Basle, Arnaud;Vita, Nicolas;Dennison, Christopher;Subtilis, Bacillus
  • 通讯作者:
    Subtilis, Bacillus

Dennison, Christopher的其他文献

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{{ truncateString('Dennison, Christopher', 18)}}的其他基金

Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
  • 批准号:
    RGPIN-2018-04253
  • 财政年份:
    2022
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Discovery Grants Program - Individual
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
  • 批准号:
    RGPIN-2018-04253
  • 财政年份:
    2021
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Discovery Grants Program - Individual
Biomedical Instrumentation
生物医学仪器
  • 批准号:
    CRC-2017-00050
  • 财政年份:
    2021
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Canada Research Chairs
Towards an advanced head surrogate for blunt impact assessment in defense injury scenarios
寻找一种先进的头部替代物,用于防御伤害场景中的钝器撞击评估
  • 批准号:
    554461-2020
  • 财政年份:
    2021
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Alliance Grants
Towards an advanced head surrogate for blunt impact assessment in defense injury scenarios
寻找一种先进的头部替代物,用于防御伤害场景中的钝器撞击评估
  • 批准号:
    554461-2020
  • 财政年份:
    2020
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Alliance Grants
Biomedical Instrumentation
生物医学仪器
  • 批准号:
    CRC-2017-00050
  • 财政年份:
    2020
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Canada Research Chairs
Biomedical Instrumentation
生物医学仪器
  • 批准号:
    CRC-2017-00050
  • 财政年份:
    2019
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Canada Research Chairs
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
  • 批准号:
    RGPIN-2018-04253
  • 财政年份:
    2019
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Discovery Grants Program - Individual
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
  • 批准号:
    RGPIN-2018-04253
  • 财政年份:
    2018
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Discovery Grants Program - Individual
Biomedical Instrumentation
生物医学仪器
  • 批准号:
    CRC-2017-00050
  • 财政年份:
    2018
  • 资助金额:
    $ 2.33万
  • 项目类别:
    Canada Research Chairs

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Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
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用于工程保护装置生物力学评估的新型仪器和模型
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Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
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