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Metabolic manipulation of hypoxia for improved radiotherapy response

Metabolic manipulation of hypoxia for improved radiotherapy response
缺氧的代谢控制可改善放疗反应
批准号：
451372
负责人：
Minchinton Andrew I
金额：
$49.32万
依托单位：
B.C. Cancer Research Centre (Vancouver)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-09-01 至 2025-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=451372&lang=en
关键词：
Drug Screening Glycolytic Blockade Hypoxia Metabolic Reprogramming Mitochondria Inhibitors Prodrugs Radiotherapy Re-Oxygenation Respiratory Chain Inhibitors Tumour Microenvironment

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英文摘要
Despite over a hundred years of research there is still no Health Canada/FDA approved drug that can be taken at the time of radiotherapy to improve treatment outcome without increasing side effects in non-cancer tissues. Radiotherapy improvements have lar
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