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Development of clinical candidate hypoxia-activated DNA-PK inhibitors

Development of clinical candidate hypoxia-activated DNA-PK inhibitors
临床候选缺氧激活 DNA-PK 抑制剂的开发
批准号:
490356
负责人:
Minchinton Andrew I
金额:
$71.33万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2027-09-01

项目摘要

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翻译
放疗和化疗仍然是无法手术的癌症的主要治疗方法。在这些疗法之后,癌细胞会被杀死,但由于它们修复DNA损伤的能力,一些癌细胞会产生抗药性。最近,药物可以阻止癌细胞的能力
英文摘要
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FLASH radiotherapy - mechanisms and translational studies
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