Metabolic manipulation of hypoxia and radiotherapy response

缺氧和放疗反应的代谢调控

• 批准号: 293382
• 负责人: Minchinton Andrew I
• 金额: $ 52.97万
• 依托单位: BC Cancer, part of PHSA (Vancouver)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-09-01 至 2018-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=293382&lang=en
• 关键词: Hypoxia; Metabolism; Radiation

As cancers grow they often outstrip their blood supply which leads to hypoxic regions in tumours, where cells exist at low oxygen tension. Low oxygen status within tumours has long been known to have a profound effect on tumour aggressiveness and radiati

随着癌症的生长，它们通常超过其血液供应，这导致肿瘤中的缺氧区域，其中细胞存在于低氧张力下。肿瘤内的低氧状态长期以来被认为对肿瘤的侵袭性和放射性有深远的影响。