Development and optimization of a portable COVID-19 detection device for wastewater applications

用于废水应用的便携式 COVID-19 检测装置的开发和优化

• 批准号: 567167-2021
• 负责人: Goodwin, Brett
• 金额: $ 1.82万
• 依托单位: Sir Sandford Fleming College of Applied Arts and Technology
• 依托单位国家: 加拿大
• 项目类别: Applied Research and Development Grants - Level 1
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=724121
• 关键词: Development; optimization; portable; COVID; 19

Measuring SARS-CoV-2 RNA in wastewater provides critical information to governing agencies on the potential COVID-19 risks their communities face. Rapid monitoring tools are becoming increasingly important in the ability to detect these occurrences quickly and accurately. FREDsense Technologies Corp. (FREDsense) is a Canadian company based out of Calgary, Alberta, specializing in the development of innovative water quality field testing kits. In collaboration with Fleming College's Centre for Advancement of Water and Wastewater Technologies (CAWT) this applied research project will focus on the optimization of FREDsense's newest technology used to detect the SARS-CoV-2 virus in wastewater. This applied research project will first focus on establishing the device's virus detection capabilities in pure water and then in real world wastewater samples. As the project progresses and data is analyzed, recommendations and modifications to the device will be made to improve performance in terms of detection capacity, as well as identifying and correcting for interfering substances found in wastewater. The device's performance will be compared to the standard and widely used RT-qPCR method. These results will allow FREDsense to further develop and refine their technology and accelerate their market entry plans.

测量废水中的SARS-CoV-2 RNA为管理机构提供了有关其社区面临的潜在COVID-19风险的关键信息。快速监测工具在迅速和准确地检测这些事件的能力方面变得越来越重要。 FREDsense Technologies Corp.（FREDsense）是一家位于加拿大阿尔伯塔省卡尔加里市的加拿大公司，专门开发创新的水质现场测试套件。 与弗莱明学院的水和废水技术促进中心（CAWT）合作，该应用研究项目将重点关注FREDsense用于检测废水中SARS-CoV-2病毒的最新技术的优化。该应用研究项目将首先专注于建立该设备在纯水中的病毒检测能力，然后在真实的世界废水样本中进行检测。 随着项目的进展和数据的分析，将对设备提出建议和修改，以提高检测能力，以及识别和纠正废水中发现的干扰物质。该设备的性能将与标准和广泛使用的RT-qPCR方法进行比较。 这些结果将使FREDsense能够进一步开发和完善其技术，并加快其市场进入计划。