根据中国社会文化特点，修订Buss A.H & Durkee A编制的Aggression Questionnaire(AQ)，并制定中国9～18岁农村学生AQ常模。以AQ中国城乡常模诊断攻击个体，应用1：1病例对照研究，结合前期研究收集的样本，在知情同意的基础上选择攻击与非攻击学生各500例，采用高通量基因分型系统OpenArray分析攻击行为青少年MAOA、 Nr2e1、APP、Dysbindin、MMP-9、B-CK基因多态性及其与非攻击青少年的差异，并确定其异常部位，借以探讨攻击行为发生、发展的分子遗传学机制；运用非参数统计方法（如联合分区法）进行基因-基因、基因-行为的交互作用分析，探讨基因- - 行为的作用机制。

To revise Aggression Questionnaire (AQ) formating by Buss A.H and Durkee A according to the social and cultural characteristics in China rural areas, and make AQ norms of 9 ~ 18 years old countryside student in China. Aggressive individuals were screened and diagnosed by AQ China norms. Combined with the collection of sample before, one thousand individuals (five handred aggressive individuals and no aggressive individuals , respectively)were choosed on informed consent, and 1:1 case control study was used. The high throughput genotyped system OpenArray was used to analysis the gene-polymophism and differences of monoamine oxidase A (MAOA), Nuclear receptor subfamily 2, group E, member 1(Nr2e1), Amyloid precursor protein (APP), Dysbindin, Matrix metalloproteinase-9 (MMP-9), Brain-type creatine kinases(B-CK) genes between aggressive and no aggressive individuals,and determine the abnormal spot, so as to explore the molecular genetics mechanism of aggressive behavior happened and development.Use non-parameter statistics analysis the interaction between gene-gene and gene-behavior , in order to explore the mechanism of action of genes- - behavior.