Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors.
Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors.
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累积风险评估：评估从暴露到多种环境压力源的健康效果的方法学方法的概述。
DOI：
10.3390/ijerph9020370
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发表时间：
2012-02
影响因子：
--
通讯作者：
Sexton K
中科院分区：
文献类型：
--
作者：
Sexton K
对多种环境压力因素综合影响造成的累积健康风险进行系统评估正在成为旨在保护人口和社区的基于风险的决策的重要组成部分。本文简要回顾了累积风险评估作为分析工具的历史发展，并讨论了评估化学混合物以及化学和非化学压力源组合对累积健康影响的当前方法。比较了基于压力源和基于效果的评估方法，并讨论了关注可行的风险管理选项以限制累积评估范围的潜在价值。累积风险评估的最终目标是基于有组织的科学分析，为决策相关问题提供答案；即使答案至少目前是不准确且不确定的。
Systematic evaluation of cumulative health risks from the combined effects of multiple environmental stressors is becoming a vital component of risk-based decisions aimed at protecting human populations and communities. This article briefly examines the historical development of cumulative risk assessment as an analytical tool, and discusses current approaches for evaluating cumulative health effects from exposure to both chemical mixtures and combinations of chemical and nonchemical stressors. A comparison of stressor-based and effects-based assessment methods is presented, and the potential value of focusing on viable risk management options to limit the scope of cumulative evaluations is discussed. The ultimate goal of cumulative risk assessment is to provide answers to decision-relevant questions based on organized scientific analysis; even if the answers, at least for the time being, are inexact and uncertain.
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影响因子：
10.4
作者：
DeFur PL;Evans GW;Cohen Hubal EA;Kyle AD;Morello-Frosch RA;Williams DR
通讯作者：
Williams DR
影响因子：
10.4
作者：
Carpenter DO;Arcaro K;Spink DC
通讯作者：
Spink DC
DOI：
10.3390/ijerph8114220
发表时间：
2011-11
影响因子：
--
作者：
Yorita Christensen KL;White P
通讯作者：
White P
影响因子：
10.4
作者：
Callahan, Michael A.;Sexton, Ken
通讯作者：
Sexton, Ken
影响因子：
5.4
作者：
Erren, TC;Jacobsen, M;Piekarski, C
通讯作者：
Piekarski, C