Acquistion of a Zeiss Axiophot Photomicroscope

这是一个请求资金获得荧光 这台显微镜将主要由两个研究小组使用。 一个小组正在研究人类 上皮细胞相互识别并粘附。 过程 似乎是由一个完整的膜蛋白， 已被纯化并产生了抗体。 第二个研究小组正在研究与这种转变有关的蛋白质 寄生蠕虫的有氧代谢和无氧代谢之间的关系。 线粒体蛋白质已经被纯化， 这里也产生了。 两项研究中的抗体将 荧光标记，然后用作探针定位 细胞结构中感兴趣的蛋白质，使用 要求仪器。

This is a request for funds to obtain a fluorescence microscope that will be used primarily by two research groups. One group is investigating the mechanism by which human epithelial cells recognize and adhere to each other. The process seems to be mediated by an integral membrane protein which has been purified and against which antibodies have been produced. The second group is investigating proteins involved in the shift between aerobic and anaerobic metabolism in parasitic helminths. Mitochondrial proteins have been purified and antibodies generated here also. The antibodies in both studies will be fluorescently labelled and then used as probes to localize the proteins of interest in the cellular structures, using the requested instrumentation.