Jeol Jem-1200EX Bio Transmission Electron Microscope

这项提议是为了获得一个高分辨率的透射电子显微镜(JEOL JEM-1200EX-BIO)，以取代已有20年历史的JEM-100B，JEM-100B目前是向加州大学圣地亚哥分校(UCSD)的生物研究人员提供的两个标准传输电子之一。这些显微镜和标本制备设施一起构成了加州大学圣地亚哥分校医学院的神经细胞学实验室，该实验室是在充电的基础上运营的。目前有20多个研究项目，涉及12名资深调查人员，依赖于使用神经细胞学实验室的电子显微镜设施。主要用户群由主要来自医学院的资深科学家组成，他们对神经生物学有研究兴趣。一般校园或联合机构的其他用户也受益于冷冻骨折、三维重建或冷冻切割的特殊设施，这些设施在该地理区域的其他地方不能以充值方式使用。

This proposal is to obtain a high resolution transmission electron microscope (JEOL JEM-1200EX-BIO) to replace a 20 year- old JEM-100B which is currently one of two standard transmission electron provided as "core facilities" to biological investigators at the University of California at San Diego (UCSD). These microscopes, along with facilities for specimen preparation, constitute the Laboratory for Neurocytology that is operated on a recharge basis in the School of Medicine at UCSD. There are over 20 research projects involving 12 established investigators currently dependent on the use of the electronmicroscopic facilities of the Laboratory for Neurocytology. The major user group consists of established scientists mainly from the School of Medicine with research interests in neurobiology. Other users from the general campus or the allied institutions also benefit from the special facilities for freeze-fracture, three-dimensional reconstruction, or cryosectioning, not available for use on a recharge basis elsewhere in this geographic area.