JEOL JEM-1400 Transmission Electron Microscope for the University of South Caroli

描述（由申请人提供）：本申请要求资金为一组9名NIH资助的研究人员购买JEOL 1400透射电子显微镜，用于南卡罗来纳州大学、南卡罗来纳州医科大学和弗吉尼亚理工大学Carillion校区。研究人员共有19项NIH赠款，用于心血管疾病、阿尔茨海默病研究和使用替代药物减少炎症。所要求的仪器将取代一台使用了28年的JEOL 200CX透射电子显微镜，该显微镜经历了一系列维护问题，导致仪器在21%的时间内无法正常工作。所要求的仪器将放置在位于医学院校园内的南卡罗来纳州大学仪器资源设施（IRF）。JEOL 1400具有通过图形用户界面进行远程操作的能力，这将大大增强弗吉尼亚理工大学Carillion和南卡罗来纳州医科大学研究人员的研究。IRF是一个核心生物技术设施，拥有广泛的设备，现有的行政和研究人员，以及大学的大力支持。IRF主任和本提案的主要研究者Robert Price博士正在与参与本提案的所有研究者进行电子显微镜合作。

DESCRIPTION (provided by applicant): This application requests funds to purchase a JEOL 1400 transmission electron microscope for a group of 9 NIH funded investigators to be used at the University of South Carolina, the Medical University of South Carolina and the Virginia Tech Carillion campus. Together the investigators have 19 active NIH grants for research in cardiovascular disease, Alzheimer's research, and use of alternative medicines to reduce inflammation. The requested instrument will replace a 28 year old JEOL 200CX transmission electron microscope that has experienced a series of maintenance problems that have resulted in the instrument being nonfunctional 21% of the time. The requested instrument will be placed in the University of South Carolina Instrumentation Resource Facility (IRF) located on the School of Medicine campus. The JEOL 1400 has capability through the Graphical User Interface to be operated remotely which will significantly enhance the research of the investigators at Virginia Tech Carillion and the Medical University of South Carolina. The IRF is a core biotechnology facility with a wide range of equipment, an existing administrative and research staff, and strong support from the University. Dr. Robert Price, Director of the IRF and PI of this proposal, has ongoing electron microscopy collaborations with all of the investigators participating in the proposal.