Acquisition of a High Performance Liquid Chromatography (HPLC) Instrument

我们正在为一个多研究者色谱系统申请资金，该系统由一个具有光电二极管阵列(PDA)能力的高效液相色谱(HPLC)仪器组成。该仪器将为教职员工和学生提供使用最先进的设备，这些设备是目前不断增长的研究计划所需的。具体地说，该仪器将被多个研究人员用于下列研究问题：(1)Sabine-Neches河口有机物的生物地球化学循环；(2)调节蚯蚓水平衡的神经内分泌因子的分离；(3)环境中有机分子的化学去向研究；(4)软体动物免疫生物学研究。大分子的分离和提纯对所有这些项目都是至关重要的，而高效液相色谱法将提供这一能力。光电二极管阵列探测器将允许识别复杂混合物中的分子，特别是在自然系统中工作时。

We are requesting funds for a multi-investigator chromatography system which consists of a high performance liquid chromatography (HPLC) instrument with photodiode array (PDA) capability. The instrumentation will provide faculty and students with use of state-of-the-art equipment that is needed at this time for a growing research program. Specifically, this instrument is to be used by multiple investigators on the following research problems: (1) biogeochemcial cycling of organic matter in the Sabine-Neches estuary; (2) isolation of the neuroendocrine factors regulating water balance in the earthworm; (3) chemical fate studies of organic molecules in the environment; (4) studies on molluscan immunobioloby. The separation and purification of macromolecules is of prime importance to all of these projects, and HPLC would provide this capability. The photodiode array detector will allow for identification of molecules in complex mixtures, particularly when working in natural systems.