Joint Implant Surfaces

本研究的目的是设计微机械 用于整形外科植入装置的图案化表面， 选择性地引起以下类型的反应：1） 促进骨和限制软组织向内生长， 区域; 2）增强软组织生长，同时抑制骨 生长;以及3）充当软组织向内生长的屏障 进入骨骼附着区。 的组合 将测试微几何形状的能力， 鼓励和/或阻止特定部位的组织向内生长 从而获得寿命更长的髋关节成形术装置。 关节骨附着面的改进设计 植入装置将提供改进的可销售产品。 骨科关节植入物领域预计将增长 在未来10年内每年增长20%， 每年进行40万例全髋关节置换术。

The goal of this research is to design micromachined patterned surfaces for orthopaedic implant devices that selectively cause the following types of reactions: 1) promote bone and restrict soft tissue ingrowth in critical regions; 2) enhance soft tissue growth while inhibiting bone growth; and 3) act as a barrier for soft tissue ingrowth into bone attachment areas. Combinations of the microgeometries will be tested for their ability to encourage and/or discourage site-specific tissue ingrowth and thus achieve a longer-lived hip arthroplasty device. The enhanced design of bone attachment surfaces for joint implant devices will provide an improved marketable product. The field of orthopaedic joint implants is projected to grow at 20% per year over the next 10 years with currently over 400,000 total hip arthroplasties performed annually.