Two-Dimensional Polymerizations in Supramolecular Assemblies

9400369 O‘Brien在过去的十年中介绍了几种聚合超分子组件的方法。许多这样的组装体，例如单层、脂质体和多层，都是两亲分子的二维阵列。从这些组件中成功地设计和可重复制备新材料需要对聚合过程有清楚的了解。以前由NSF-DMR支持的研究已经成功地提供了对超分子快速扩散区域中两亲分子线性聚合的本质的基本理解。将继续进行的新研究将表征交联聚合以及慢扩散区域中的聚合。本实验室开发的方法将用于表征新设计的双功能分子在二维组件中的交联效率。在高于(快速扩散)和低于(缓慢扩散)双层组件的主相变温度的温度下，将比较双层中的聚合速率和聚合度。这些双层膜的研究结果将被用于设计新的单体，用于其他超分子的聚合，例如盘状液晶。超分子组装体的聚合提供了一种有效的手段来修饰它们的化学和物理性质，以制备具有生物和材料科学都感兴趣的特殊性质的新型材料。到目前为止的研究表明，聚合的超分子组装体可能在诊断、试剂和药物的控制输送、设计和制备有效传递光能的稳定组装体、表面改性和有机沸石的稳定方面具有实用价值。***

9400369 O'Brien Several methods to polymerize supramolecular assemblies were introduced in the last decade. Many of these assemblies, e.g. monolayers, liposomes, and multilayers, are two-dimensional arrays of amphiphiles. Success in the design and reproducible preperation of new materials from these assemblies requires a clear understanding of the polymerization processes. The previous studies suppported by NSF-DMR have successfully provided a basic understanding of the nature of linear polymerizations of amphiphiles in the supramolecular fast-diffusion regime. The new research to be carried over will characterize crosslinking polymerizations as well as polymerizations in the slow-diffusion regime. Methods developed in this laboratory will be used to characterize the efficiency of crosslinking in two-dimensional assemblies with newly designed bifunctional molecules. The rate and degree of polymerization in bilayers will be compared at temperatures above (fast diffusion) and below (slow diffusion) the main-phase transition temperature of the bilayer assembly. These results of these studies on bilayers will be used to design new monomers for the polymerization of other supramolecular, e.g. discotic liquid crystals. %%% The polymerization of supramolecular assemblies provides an effective means to modify their chemical and physical properties to prepare novel materials with particular properties of interest to both biological and material sciences. The research to date indicates that polymerized supramolecular assemblies are likely to find utility in diagnostics, in the controlled delivery of reagents and drugs, in the design and preparation of stable assemblies for the efficient transduction of light energy, in surface modification, and for the stabilization of organic zeolites. ***