Acquisition of the First Tandem Mass Spectrometer for New Orleans

项目提案：9512155 PI: Cole， R.资助机构：美国新奥尔良大学这项来自学术研究基础设施项目的资助将帮助新奥尔良大学化学系获得用于研究的三重四轴质谱仪。拟资助的研究活动包括：1。直接混合分析细菌毒素，和脂质部分2。新型鞘糖脂的结构分析问题3。能量分辨串联质谱实验有机金属化合物的热力学性质光收集蛋白的氨基酸序列碰撞激活反应质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。电喷雾技术的加入将质谱的范围扩展到蛋白质和核酸分子量，远远超出任何其他技术。电喷雾电离的使用与高分辨率相结合，为质谱分析提供了最新的技术。它为化学家提供了表征化合物的最有力的工具之一。在质谱法中获得这种能力对于化学许多领域的前沿研究的进行是必不可少的。

ABSTRACT Proposal: 9512155 PI: Cole, R. Institution: University of New Orleans This award from the Academic Research Infrastructure Program will help the Department of Chemistry at the University of New Orleans acquire triple quadrapole Mass Spectrometer which will be used in research. The research activity to be supported includes: 1. direct mixture analysis of bacterial toxins, and lipid portions 2. structural analysis problems involving novel glycosphingolipids 3. energy-resolved tandem mass spectrometry experiments 4. thermodynamic properties of organometallic compounds 5. amino acid sequence of light harvesting proteins 6. collisionally-activated reactions 7. reactivity of Zintl phase materials Mass Spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic and organometallic molecules. The addition of the technique of electrospray extends the range of MS to protein and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization is combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.