NMR Facility Modernization

摘要提案：9512197 PI: Lynn， D.G.机构：芝加哥大学这份来自学术研究基础设施计划的奖励将帮助芝加哥大学化学系获得500 MHz， 300 MHz和400 MHz核磁共振控制台。拟资助的研究活动包括：1。热休克蛋白的保护机制变色龙两亲肽核酸结合蛋白（包括锌指等金属结合基序）和核酸的结构和机制；均相催化基础化学5。螯合14族分子框架的合成、结构与性质构象明确的聚合物和微相分离嵌段共聚物核磁共振（NMR）波谱是化学家用来研究分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果在聚合物和催化以及生物学等领域都很有用。

ABSTRACT Proposal: 9512197 PI: Lynn, D.G. Institution: University of Chicago This award from the Academic Research Infrastructure Program will help the Department of Chemistry at the University of Chicago acquire consoles for a 500 MHz, 300 MHz, and 400 MHz NMR. The research activity to be supported includes: 1. mechanism of protection by heat shock proteins 2. Chameleonic Amphiphilic Peptides 3. the structure and mechanism of nucleic-acid binding proteins (including metal-binding motifs such as Zn fingers) and of nucleic acid 4. basic chemistry of homogeneous catalysis 5. Synthesis, Structures, and Properties of Catenated Group 14 Molecular Frameworks 6. Conformationally Well-Defined Polymers and Micro-phase Separated Block Copolymers Nuclear Magnetic Resonance (NMR) Spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in areas such as polymers and catalysis, and in biology.