Utilization of GC/MS in an Undergraduate Chemistry Curriculum

该项目资助购买最先进的气相色谱/质谱仪（GC/MS）用于本科化学教学。这种仪器的增加影响了许多本科课程，包括普通化学、有机化学、物理化学和仪器分析。许多新的实验被引入到本科课程中。特别是，这些实验(1)向学生介绍质谱的理论，并展示电子冲击和化学电离光谱的各个方面；(2)向学生传授质谱碎片图表征结构的基础知识；(3)为学生提供气相色谱/质谱的实践经验，并提供接触现代计算机辅助设备的机会；(4)让学生有机会使用谱库搜索例程；(5)向学生展示串联分析方法的应用以及这些技术在混合物分析中的应用。

This project is funding the purchase of a state-of-the-art Gas Chromatography/Mass Spectrometer (GC/MS) for undergraduate instruction in chemistry. Addition of this instrumentation affects many of the undergraduate courses, including General Chemistry, Organic Chemistry, Physical Chemistry, and Instrumental Analysis. Many new experiments are being introduced into the undergraduate curriculum. In particular, these experiments (1) give students an introduction to the theory of mass spectrometry and demonstrate a variety of aspects of electron impact and chemical ionization spectra; (2) teach students the basics of structural characterization by mass spectral fragmentation patterns; (3) give students hands-on experience with a GC/MS and provide exposure to modern computer-assisted equipment; (4) give students the opportunity to use spectral library searching routines; and (5) show students the application of tandem analytical methods and the utility of these techniques for mixture analysis.