Acquisition of a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

化学研究仪器和设施(CRIF)计划和主要研究仪器(MRI)计划的这一奖项将使加州大学伯克利分校的化学系能够获得配备电喷雾和基质辅助激光解吸电离的傅立叶变换离子回旋共振质谱仪。该设备将加强研究，包括高对称性超分子组装的预设计、合成和研究、过渡金属簇合物的合成和研究、金属配位低聚糖的立体化学分化、异双金属有机金属配合物的合成和研究、半导体纳米晶体和高电荷树枝状大分子的分析作为超分子结构的基石。质谱学是一种用于探测大量有机、生物有机和有机金属分子的密切结构细节和获得其分子组成的技术。这些研究中将要进行的多电荷多金属配位生物分子和聚合物的分析需要高质量、高分辨率和高质量精度，使用傅立叶变换离子回旋质谱仪与电喷雾和基质辅助激光解吸电离相结合。在质谱学中获得这种能力对于开展许多化学领域的前沿研究是至关重要的。

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Major Research Instrumentation (MRI) Program will enable the Department of Chemistry at The University of California in Berkeley to acquire a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer equipped with both electrospray and matrix assisted laser desorption ionization. This equipment will enhance research which includes pre-design, synthesis and study of high symmetry supramolecular assemblies, synthesis and study of transition metal cluster compounds, stereochemical differentiation of metal-coordinated oligosaccharides, synthesis and study of heterobimetallic organometallic complexes, analysis of semiconductor nanocrystals and highly charged dendrimers as building blocks for supramolecular structure. Mass spectrometry is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. Analysis of the multiply charged multiple metal coordinated biomolecules and polymers to be carried out in these studies requires the high mass, high resolution and high mass accuracy available using the combination of fourier transform ion cyclotron mass spectrometry with electrospray and matrix assisted laser desorption ionization. The acquisition of this capability in mass spectrometry is essential for carrying out frontier research in many fields of chemistry.