Isomerizations of Isotopically Labeled Hydrocarbons

本项目探索相对较小的碳氢化合物分子的热反应机理，以更深入地探索将其转化为其他结构的化学转化的特征。这些小分子的类似物将被贴上稳定同位素的标签，作为反应物中的标记物。通过确定所形成的产物中同位素标签的位置，可以对反应本身有一个更全面的认识。对反应机制的见解和对理论的刺激，基于分子量子力学的理解反应的尝试将会产生。有了这个奖项，有机和大分子化学项目将继续支持雪城大学约翰·e·鲍德温教授的研究。鲍德温教授选择了涉及相对小分子的有趣反应的例子。合成这些分子时，在特定位置加入碳和/或氢的非放射性同位素，然后进行感兴趣的反应。通过追踪同位素的命运，可以收集到反应发生的每一分钟的信息，从而更全面地了解科学家所说的“化学反应”的基本性质。

This project explores the mechanism of thermal reactions of relatively small hydrocarbon molecules in order to probe more deeply the characteristics of the chemical transformations which convert them into other structures. Analogs of these small molecules will be labelled with stable isotopes, which will serve as markers in the reactants. A more comprehensive view of the reactions themselves may be gained through determining the disposition of isotopic labels in the products formed. Insights as to reaction mechanisms and a stimulus to theoretical, molecular quantum mechanics-based attempts to comprehend the reactions will result.With this Award, the Organic and Macromolecular Chemistry Program continues support for the research of Professor John E. Baldwin of Syracuse University. Professor Baldwin selects examples of reactions of interest involving relatively small molecules. These molecules are synthesized while incorporating a nonradioactive isotope of carbon and/or hydrogen at specific sites, and the reaction of interest is then carried out. By tracking the fate of the isotope, information into the minute goings-on of the reaction can be gathered, building toward a fuller understanding of the fundamental nature of what scientists refer to as a "chemical reaction."