FASEB Conference: Transport Atpases to be held in Snowmass, Colorado on July 3-8, 1999

9903531Pedersen1999年7月3日至8日在科罗拉多州斯诺马斯举行的FASEB运输ATPase会议聚集了世界各地的研究人员，讨论与这些重要酶的结构、功能和机制有关的基础研究成果，以及它们在许多生理过程中的作用。这些包括离子平衡、激素储存、细胞pH调节、骨形成、氧化磷酸化和细胞器生物发生。其中包括已被广泛研究的Na/K ATPase、钙ATPase和质子ATPase，以及近几年才受到关注的ABC转运子超家族ATPase和铜转运ATPase。重点将放在运输ATPase研究的最新进展上，其中将包括许多仍未发表的正在进行的工作。会议旨在进行一系列讲座、讨论和海报演示，其中将包括成熟的调查人员、刚开始他们职业生涯的初级调查人员以及在该领域工作的博士后研究员和研究生。会议的联合主席是瑞士苏黎世瑞士联邦理工学院教授Ernesto Carafoli和马里兰州巴尔的摩约翰霍普金斯大学教授Peter Pedersen。这次会议汇集了来自世界各地的初级、职业中期和高级研究人员，以及美国运输ATPase的一些博士后研究员和研究生。它们有助于将营养物质移入和移出细胞和亚细胞室。值得注意的是，移动(运输)需要能量。在生物系统中，这种能量储存在一种叫做三磷酸腺苷(ATP)的分子中。当三磷酸腺苷与运输蛋白结合时，它会释放能量，帮助营养物质进入细胞和它们的隔间，以及其他物质从它们的隔间和细胞外。活细胞生存所需的营养物质有很多种。因此，一些转运ATPase可能转运钠，另一些转运钙，还有一些转运磷酸盐。这次会议的目的是让演讲、讨论和海报演示很好地结合在一起。将要讨论的实验与农业有相当大的相关性，例如与提高作物产量和改善动物营养有关。

9903531PedersenThe FASEB conference on transport ATPases held at Snowmass Colorado, July 3 -8, 1999 brings together investigators throughout the world to discuss basic research findings relevant to the structure, function, and mechanism of these important enzymes, and their roles in numerous physiological processes. These include ion balance, the storage of hormones, the regulation of cell pH, bone formation, oxidative phosphorylation, and organelle biogenesis. Among the transport ATPases systems discussed are those which have been extensively studied, like the Na/K ATPase, the calcium ATPases, and the proton ATPases, and those which have come into the limelight only in recent years, e.g., the ABC transporter superfamily of ATPases, and the copper transporting ATPases. The focus will be on the newest developments at the cutting edge of transport ATPase research, which will include much work in progress that is still unpublished. The meeting is designed to have a good mixture of lectures, discussion, and poster presentations, which will include established investigators, junior investigators commencing their careers, and postdoctoral fellows and graduate students working in the field. The co-chairman of the meeting are Ernesto Carafoli, Professor, Swiss Federal Institute of Technology, Zurich, Switzerland, and Peter Pedersen, Professor, Johns Hopkins University, Baltimore, Maryland. This conference brings together junior, mid-career, and senior investigators from throughout the world, and a number of postdoctoral fellows and graduate students in the U.S. Transport ATPase are proteins that are located in the membranes of animal, plant, and bacterial cells. They help move nutrients into and out of cells and subcellular compartments. Significantly, moving (transporting) requires energy. In biological systems this energy is stored in a molecule called ATP (adenosine triphosphate). When ATP binds to the transport protein it releases its energy which helps drive the nutrients into cells and their compartments and other substances out of their compartments and out of the cells. There are many types of nutrients that living cells need to survive. Therefore, some transport ATPases may transport sodium, others calcium, and still others phosphate. The meeting is designed to have a good mixture of lectures, discussion, and Poster presentations. The experiments to be discussed have considerable relevance to agriculture, e.g. to increasing crop yields and to improving animal nutrition.