New Roles for Soluble Polymers in Homogeneous Catalysis

大卫教授E.德克萨斯农工大学化学系的Bergbreiter因其对可溶性聚合物在均相催化中的新作用的研究而得到有机和大分子化学项目的支持。通过设计具有可调溶解度的聚合物载体，Bergbreiter教授将开发出允许聚合物结合的催化剂用于各种金属催化反应（包括Heck反应，Suzuki偶联和烯烃异构化）的简单分离，回收和再利用的方案。多价互聚物氢键将被检查作为一种方法来形成不溶性的，可回收的聚合物凝胶。两种不同的负载型催化剂或金属络合物的最小互聚物相互作用的条件将通过变温31P NMR光谱来定义，该研究还将提供对聚合物内络合的深入了解。这些研究的结果，再加上可溶性聚合物提供的溶解度控制，将被用于开发新的组合方法来测试催化剂。虽然可溶性催化剂提供了许多优势，他们不溶性的同行，他们往往很难从他们的反应所需的产品分离，一个关于产品的污染和催化剂的回收或再利用的困难的问题。在有机与大分子化学项目的支持下，大卫E.德克萨斯A M大学化学系的Bergbreiter正在开发一种方案，该方案允许将聚合物结合的催化剂容易地分离、回收和再利用于各种金属催化反应。

Professor David E. Bergbreiter, of the Department of Chemistry at Texas A&M University, is supported by the Organic and Macromolecular Chemistry Program for his studies of new roles for soluble polymers in homogeneous catalysis. By designing polymer supports with tunable solubility, Professor Bergbreiter will develop schemes permitting the facile separation, recovery, and reuse of the polymer-bound catalysts for various metal-catalyzed reactions, including the Heck reaction, Suzuki coupling, and alkene isomerization. Polyvalent interpolymer hydrogen-bonding will be examined as an approach to the formation of insoluble, recoverable polymer gels. The conditions for minimal interpolymer interaction of two different supported catalysts or metal complexes will be defined by variable temperature 31P NMR spectroscopy, studies which will also provide insight into intrapolymer complexation. The results of these studies, coupled with the solubility control afforded by soluble polymers, will be used to develop new combinatorial approaches to catalyst testing.While soluble catalysts offer many advantages over their insoluble counterparts, they are often difficult to separate from the desired products of their reactions, a problem with regards to both contamination of the products and difficulty in recovery or reuse of the catalyst. By exploring polymeric supports for catalysts which are soluble under desired reaction conditions but are rendered insoluble or easily separable under appropriate conditions by their detailed structures, and with the support of the Organic and Macromolecular Chemistry Program, Professor David E. Bergbreiter, of the Department of Chemistry at Texas A&M University, is developing schemes permitting the facile separation, recovery, and reuse of polymer-bound catalysts for a variety of metal-catalyzed reactions.