MRI: Acquisition of a 400 MHz NMR Spectrometer for Use in Research and Research Training at Reed College

在主要研究仪器(MRI)计划的这一奖励下，里德学院化学系将获得一台400 MHz核磁共振(核磁共振)光谱仪。该设备将使研究人员能够研究a)通过磁化转移的酶机制；b)过渡态模拟物的合成；c)天然产物的合成；d)糖异构酶的机理和结构研究。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Reed College will acquire a 400 MHz nuclear magnetic resonance (NMR) spectrometer. This equipment will enable researchers to carry out studies on a) enzyme mechanisms through magnetization tansfer; b) synthesis of transition-state mimics; c) natural product synthesis; and d) mechanistic and structural studies of sugar isomerases. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research.