Adaptive and Survival Strategies of Microorganisms in Biofilms

一项合作研究计划将研究生物膜中微生物的适应和生存策略。 合作小组包括布法罗大学和马尔莫大学（瑞典）的研究人员。 该计划有三个目标：作为一个明确的测试的诱导假说与一个良好的研究系统，以确定一般和酸特异性应激蛋白诱导的S。变形链球菌H7在酸耐受反应早期的作用，并对其功能进行初步研究，建立变形链球菌的酸耐受与饥饿反应之间的关系。变形链球菌，作为其作为生物膜附着的基质的表面能的函数;并扩大应激蛋白诱导的研究，包括S. mutnas的动态剪切应力，表征相关的微生物生物膜环境。

A collaborative research program will study adaptive and survival strategies of microorganisms in biofilms. The collaborating team includes researchers at the University of Buffalo and at Malmo University (Sweden). The program has three objectives: as a clear test of the induction hypothesis with a well-studied system, to identify the general and acid-specific stress proteins induced in S. mutans H7 during the early stages of the acid tolerance response and to initiate studies on their function; to establish the relationships between the acid tolerance and starvation responses in S. mutans, as functions of the surface energies of the substrata to which they have attached as biofilms; and to expand the study of the induction of stress proteins to include the response of S. mutnas to dynamic shear stresses that characterize relevant microbial biofilm environments.