Biosurface Contact and Bioadhesion Studies Using AFM: A RUI Project

使用 AFM 进行生物表面接触和生物粘附研究：RUI 项目

• 批准号: 0086218
• 负责人: Robert Baier
• 金额: $ 5.6万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0086218&HistoricalAwards=false
• 关键词: Biosurface; Contact; Bioadhesion; Studies; Using

Over a two year period, the research will focus on Biosurface Contact and Bioadhesion Studies Using Atomic Force Microscopy, using fungal spores. Other aspects of the research will address monocyte and hepatocyte adhesion to reference substrata. Surface characterization expertise at UB will supplement the research performed by Towson and Frostburg undergraduates and faculty. IUCB colleagues at the U.S. Army Biotechnology Program and at the US FDA Division of Mechanics and Materials also will participate in the program.In addition to providing quantitative, time dependent evaluations of hepatocyte, monocyte, and fungal spore attachment strengths to different substrata, this study will produce techniques that can be applied to other applications involving cell and/or particle adhesion. These techniques could be applied to the dental and medical industries, as well as environmental health issues of the paint and xerography industies.

在为期两年的时间里，研究将集中在生物表面接触和生物粘附研究使用原子力显微镜，使用真菌孢子。 其他方面的研究将解决单核细胞和肝细胞粘附参考基质。 UB的表面表征专业知识将补充Towson和Frostburg本科生和教师进行的研究。 IUCB的同事在美国陆军生物技术计划和在美国FDA的力学和材料部门也将参与program.In除了提供定量，时间依赖性评估肝细胞，单核细胞，真菌孢子附着强度不同substrata，这项研究将产生技术，可应用于其他应用涉及细胞和/或颗粒粘附。 这些技术可以应用于牙科和医疗行业，以及油漆和静电印刷行业的环境健康问题。