CAREER: Controlling Solid State Reactivity via Linear Templates

该项目的目的是开发一种方法进行固态化学合成，提供了液相的合成自由度。该方法利用分子作为线性模板，使用氢键的强度和方向性来指导反应位点的排列。这些目标包括：（1）通过开发模板和反应物的家族将方法扩展到反应同源性，以及（2）将该方法的产物应用于一类被称为倒置金属有机框架的多孔结晶材料的设计。这些材料将被设计成具有纳米级尺寸的可调孔，并带有有机功能。以固态合成这些材料的有机结构单元的能力意味着可以实现通过其他合成方法无法实现的对多孔固体的访问。该计划旨在通过校园研讨会等活动将研究理念与地方，地区和国家层面的教育相结合，向学生介绍绿色化学和材料科学。固态化学技术提供了一种环境友好的或“绿色”的替代品，以替代依赖有毒有机溶剂或具有独特性质的新分子和材料的合成工艺。例如，多孔结晶固体的设计策略受到极大关注，因为它们有望提供具有改进传统和工业上重要的无机固体如沸石的性质的材料，沸石是一类材料，

The aim of this project is to develop an approach for conducting solid state chemical synthesis that provides the degrees of synthetic freedom of the liquid phase. The method utilizes molecules, as linear templates, to direct alignment of reactive sites using the strength and directionality of hydrogen bonds. The goals include: (1) expanding the methods to reaction homology by developing families of templates and reactants and (2) applying products of the approach for the design of a class of porous crystalline materials known as inverted metal-organic frameworks. These materials will be engineered to possess tunable pores of nanoscale dimensions lined with organic functionality. The ability to synthesize the organic building blocks of these materials in the solid state means that access to porous solids not achievable by other synthetic methods may be realized. The program seeks to integrate research ideas with education at the local, regional, and national level through events such as campus workshops that introduce students to green chemistry and materials science.Solid-state chemical techniques provide an environmentally-friendly, or 'green' alternative to synthetic processes that rely on toxic organic solvents or routes to new molecules and materials with unique properties. For example, strategies for the design of porous crystalline solids are of much interest owing to their promise to deliver materials with properties that improve upon traditional and industrially important inorganic solids such as zeolites, a class of materials i