Acquisition of a 700 MHz Cryoprobe NMR

在主要研究仪器（MRI）项目的支持下，路易斯安那州立大学化学系和A&amp；M学院的Luigi G. Marzilli、Robert P. Hammer和George G. Stanley将获得一台配备先进冷冻探针技术的700 MHz核磁共振光谱仪。该设备包括一个直径5.4 cm（场强为16.43特斯拉）的700 MHz超导磁体系统，一个带滤波器的三共振逆冷冻探针，用于质子和氘锁的冷却前置放大器，以及主动屏蔽z梯度。该仪器将使以下研究项目成为可能：a)金属- dna相互作用的研究；B)使用手性聚合物进行生物分析分离；c) α， α -二取代氨基酸的β -片倾向；D)卟啉致敏剂的聚集和关联；e)四吡咯体系的核磁共振研究；F)污染物与天然有机物质膜相互作用的分子水平研究；g)双金属催化剂的原位核磁共振研究。许多地区机构（南方大学、格兰布林大学、迪拉德大学和泽维尔大学）的教师也将有机会使用这台700MHz的仪器。核磁共振（NMR）波谱是化学家用来研究分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对环境化学和生物化学产生影响。

With support from the Major Research Instrumentation (MRI) Program, Luigi G. Marzilli, Robert P. Hammer and George G. Stanley, of the Department of Chemistry at Louisiana State University and A&M College will acquire a 700 MHz NMR spectrometer equipped with advanced cryoprobe probe technology. The equipment includes a superconducting 700 MHz magnet system with 5.4 cm bore (field at 16.43 Tesla), and a triple resonance inverse cryoprobe with filters, cooled preamplifiers for proton and deuterium-lock, and actively shielded Z-gradient. This instrument will enable the following research projects: a) studies of Metal-DNA interactions; b) bioanalytical separations using chiral polymers; c) beta-Sheet propensity of alpha, alpha-disubstituted amino acids; d) aggregation & association of porphyrin sensitizers; e) NMR studies of tetrapyrrole systems; f) molecular level investigations of pollutant & membrane interactions with natural organic matter; and g) in situ NMR studies of a bimetallic catalyst. Faculty at a number of area institutions (Southern University, Grambling, Dillard and Xavier) will also have access to the 700MHz instrument. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in environmental chemistry and biochemistry.