Elucidation of the signalling pathways during fertilization in mammals

这笔赠款旨在了解受精时精子和卵子的结合如何产生可存活的胚胎：这是生物学中的一项基本事件。我们的目标是了解精子的基本信号通路，这些信号通路允许卵子成为胚胎，并已知会影响胚胎质量。因此，它们对于我们理解什么是健康的早期生活是很重要的。澳大利亚在帮助商业上重要的牲畜和濒危物种的育种计划和害虫种群的避孕计划方面了解生殖过程也有经济利益。

This grant sets out to understand how the union of the sperm and egg at fertilization generates a viable embryo: this is a fundamental event in biology. We aim to understand the basic signalling pathways from the sperm which allow the egg to become an embryo and are known to influence embryo quality. They are therefore important in our understanding of what constitutes a healthy early start to life. Australia also has economic interests in understanding the reproductive process in aiding breeding programs for commercially important livestock and endangered species and contraception programs for pest populations.