The cellular dynamics of lipid droplets: implications for obesity and biodiesel production

肥胖是一种流行病，如果不加以制止，将导致澳大利亚出现巨大的社会和经济问题。从本质上讲，人类肥胖的标志是细胞脂滴的积累。这项研究将通过提供对脂滴如何形成的基本理解而使澳大利亚受益。这将在科学层面产生直接的国际影响，也将确定治疗肥胖的新化合物和策略。拟议的研究还将为提高植物油和生物柴油的生产提供战略，从而使澳大利亚的农业和能源工业受益。

Obesity is a pandemic that if not stopped, will lead to huge social and economic problems in Australia. In essence, the hallmark of human obesity is the accumulation of cellular lipid droplets. This research will benefit Australia by providing a fundamental understanding of how lipid droplets are formed. This will have immediate international impact at the scientific level and will also identify novel compounds and strategies for treating obesity. The proposed study will also benefit Australian agriculture and energy industry by providing strategies to improve the production of plant oil and biodiesel.