Selective Extraction Into Fluorous Media

匹兹堡大学的Stephen G Weber教授得到了化学系分析和表面化学项目的支持，以开发含有特定受体的氟提取材料，用于基于非共价相互作用选择性提取分析物。 新材料表现出氟碳液体的选择性溶剂化特性和特氟龙膜的坚固性。 该项目的目标是：（1）发展对氟相中特定非共价相互作用的定量理解;（2）开发用于萃取的新型溶剂系统;（3）理解并使用氟聚合物进行分离。 这项工作的影响在于材料化学，化学合成，萃取，分离，主/客体识别和传感器开发。 从复杂混合物中提取感兴趣的化合物是在实验室和制造过程中定量分离此类化合物的关键。此外，以一定的选择性将分析物萃取到分离相中可以是传感器的基础。 该项目为参与的学生提供了一个机会，进行化学基础研究，并看到研究在真实的世界应用方面的更大影响。

Professor Stephen G Weber of the University of Pittsburgh is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to develop fluorous extraction materials containing specific receptors for the selective extraction of analytes, based on noncovalent interactions. The new materials exhibit the selective solvating properties of fluorocarbon liquids and the robustness of Teflon membranes. The goals of the project are: (1) to develop quantitative understanding of specific noncovalent interactions in fluorous phases; (2) to develop novel solvent systems for extractions; and (3) to understand and use fluorous polymers in separations. The impact of this work lies in materials chemistry, chemical synthesis, extractions, separations, host/guest recognition, and sensor development. Extraction of compounds of interest from complex mixtures is the key to the quantitative isolation of such compounds in laboratory and manufacturing processes. Also, extraction of an analyte into a separate phase with some selectivity can be the basis for sensors. The project provides an opportunity for the students involved to conduct fundamental research in chemistry, and to see the larger implications of the research in terms of real world application.