EXP-SA Colorimetric Sensors for the Detection of Explosive Materials

题目：用于检测爆炸性物质的ex - sa比色传感器spi名称：Jonathan sessler机构：德克萨斯大学奥斯汀校区提案号：0730053该研究将开发新的四硫代烯（TTF）功能化的焦吡咯和相关系统，作为许多简易爆炸装置（ied）中发现的爆炸性物质的比色传感器。这项工作涉及受体化学，不受特定传感器平台的约束。“开关接通”感应是对淬火传感器的改进，并应导致背景判别的改进。ttf -杯吡咯支架的电子性质将会发生变化，并研究这种变化对底物结合和直接颜色变化的影响。此外，还提出了基于功能化三吡唑配合物和1,3,5-苯支架的“三脚架”型受体系统的设计和合成。

TITLE: EXP-SA Colorimetric Sensors for the Detection of Explosive MaterialsPI name: Jonathan SesslerInstitution: University of Texas at AustinProposal Number: 0730053This research will develop new tetrathiafulvalene (TTF) -functionalized calixpyrroles and related systems as colorimetric sensors for explosive materials found in many improvised explosive devices (IEDs). The work addresses receptor chemistry and is not bound by a specific sensor platform. The "switch on" sensing is an improvement over quenching sensors and should lead to improvements in background discrimination. The electronic properties of the TTF-calixpyrrole scaffold will be varied, and the effects of such variations on substrate binding and the direct color change will be investigated. In addition, the design and synthesis of 'tripod' type receptor systems based on functionalized trispyrazole complexes and 1,3,5-benzene scaffolds are proposed.