EXP-SA: Receptor-Free Detection of Explosives

目的：该方案的目标是开发一种独特的多模式检测方案，该方案基于嵌入MOSFET的微悬臂梁和现场MEMS加热器的创新的电子信号传输方法。智能优点：我们建议开发一种无感受器的化学传感和识别爆炸物的方法，利用其辨别的热响应，结合全电子MOSFET信号检测，所有这些都服从大规模并行和多路检测模式，并且具有必需的传感器对爆炸物蒸气的响应的正交性。具体地说，我们计划解决以下智力挑战：1)设计和制造嵌入MOSFET的微悬臂梁传感器，它可以提供前所未有的纳米机械检测气体/蒸气的灵敏度。2)设计和制造可以在50-100毫秒内以编程方式均匀加热的MOSFET悬臂梁。3)展示具有高选择性的爆炸性组件的热形态，以便能够区分爆炸性物品中的相关蒸气种类。4)设计样品收集和快速预浓缩器单元，能够在10秒内收集爆炸物，并在10秒内再生系统。5)演示在有干扰物的情况下检测爆炸物和混合物。再加上嵌入MOSFET的微悬臂梁用于全电子信号传输和检测方法，我们相信，我们的组合方法提供了一种独特的、开箱即用的举措，用于高度选择性地检测爆炸物。广泛影响：拟议的传感器系统主题将作为NU材料世界网络(MWN)计划的一部分被纳入传感器模块，该计划覆盖数千名高中生和数百名教师，包括国防部机构。我们将利用NCLT(教师)、NSEC(REUS)和MRC(MIN)下的其他NU推广计划来吸引代表不足的学生进行研究实习和研究生支持。拟议的团队将参与当地代表性不足的学生工程学会。我们将在ASME教程模块中加入研究主题。西北大学正在与芝加哥科学与工业博物馆(CMSI)的巴里·阿帕尔博士团队合作举办纳米技术展览。我们的团队将帮助在CMSI纳米技术展览的发展中提供建议和投入，包括一个关于生化传感器的主题。总体而言，我们将帮助实现研究与UG和研究生教育、实践培训、专业发展和更广泛的社会影响的有效整合。

ABSTRACTObjective:The objective of this proposal is to develop a unique combination of multimodal detection scheme anchored by an innovative electronic signal transduction approach based on MOSFET-embedded microcantilevers coupled with in-situ MEMS heaters.Intellectual Merit: We propose to develop a receptor-free detection approach for chemical sensing and identifying explosives by exploiting their discriminating thermal response, in combination with an all-electronic MOSFET signal detection all of which are amenable to massively parallel and multiplexed mode for detection and with requisite orthogonality of sensor response to explosive vapors. Specifically, we plan to address the following intellectual challenges:1) Design and fabrication of MOSFET-embedded microcantilever sensors that can provide unprecedented sensitivity of nanomechanical detection of gases/vapors.2) Design and fabrication of MOSFET cantilevers that can be heated uniformly in a programmed manner within 50-100 milliseconds.3) Demonstration of thermal speciation of explosive components with high selectivity, to enable discrimination of relevant vapor species in explosives.4) Design of sample collection and fast preconcentrator units that can collect explosives within 10 seconds and regenerate the system within 10 seconds.5) Demonstration of detection of explosives and mixtures in the presence of interferents. Coupled with MOSFET-embedded microcantilevers for all-electronic signal transduction and detection approach, we believe that our combined approach provides for a unique and out-of-the-box initiative for highly selective detection of explosives.Broader Impact: The proposed sensor system theme will be incorporated in a sensor module as a part of Materials World Network (MWN) program at NU, which reaches thousands of high school students and hundreds of teachers, including DOD establishments. We will leverage other NU outreach programs under NCLT (teachers), NSEC (REUs) and MRC (MIN) to attract underrepresented students for research internship and graduate support. The proposed team will engage in local underrepresented student engineering societies. We will incorporate research themes in the ASME tutorial modules. Northwestern is involved in an ongoing collaboration with Dr. Barry Aprison team at the Chicago Museum of Science & Industry (CMSI) for a nanotechnology exhibit. Our team will help provide advice and input in the development of Nanotechnology exhibit at CMSI, including a theme on biochemical sensors. Collectively, we will help achieve effective integration of research with UG and graduate education, hands-on training, professional development and broader societal impact.