MRI: Acquisition of a 400 MHz NMR Spectrometer to Enhance Undergraduate Research and Research Training at Willamette University

有了这项来自主要研究仪器计划（MRI）的奖项，威拉米特大学的Andrew邓肯和同事Sarah Kirk和Joseph威廉姆森将获得一台400 MHz核磁共振（NMR）光谱仪。拟议的研究跨越有机，生物有机，物理和有机金属化学的学科。例如新霉素/氨基酸和丁卡因/cGMP偶联物的合成和表征以及烯-丙二烯闭环复分解反应机理的研究。核磁共振波谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学和生物化学产生影响。该奖项还将有助于提高妇女在科学领域的地位。

With this award from the Major Research Instrumentation program (MRI), Andrew Duncan and colleagues Sarah Kirk and Joseph Williamson from Willamette University will acquire a 400 MHz Nuclear Magnetic Resonance (NMR) spectrometer. The proposed research spans the disciplines of organic, bioorganic, physical, and organometallic chemistry. Some examples are the synthesis and characterization of neomycin/amino acid and tetracaine/cGMP conjugates and studies of the mechanism of ene-allene ring closing metathesis reactions.Nuclear Magnetic Resonance spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry. This award will also contribute to the advancement of women in science.