EFRI-BSBA: Multifunctional Materials and Devices for Distributed Actuation and Sensing

名称：Konstantin KornevInstitution: Clemson UniversityProposal No 0937985摘要：蝴蝶和飞蛾，构成鳞翅目，启发了数十年的空气动力学，光学和导航工程研究。本项目重点研究鳞翅目的喙部，从工程角度对鳞翅目的喙部研究较少。目标是开发受鳞翅目流体系统启发的基于纤维的微流体的基本原理，并将这些原理应用于设计、制造和操纵一类新的基于纤维的设备，这些设备能够运输和探测以前不可能的液体范围。这些原理将使用鳞翅目的生物学数据进行验证。通过工程师、化学家和生物学家的合作，将利用现代纤维技术制造出仿生长鼻，这种技术为纤维提供了多种功能，如机械/电磁记忆、改善的吸收性和可控制的润湿性。一种仿生方法将被开发用于驱动，传感和控制的合成鼻。人工喙探测来自单个血管平滑肌细胞的液体的优点将被说明。鳞翅目流体系统被设想为将当前的微流体范式从固定的通道状结构转变为基于纤维的微流体装置，提供分布式驱动、传感和微量流体操作。该项目将在生物学、化学、材料科学、机械、电气和生物工程的界面上，作为新科学、工程和技术发展的催化剂。由一个多学科小组确定的基本原理将影响多个领域，包括(i)综合生物学（通过深入了解鳞翅目流体系统的物理功能），（ii）材料科学（通过提供关于流体-纤维相互作用和相关纤维设计参数的新知识），（iii）机器人技术和控制（通过开发形状和流体控制的仿生方法）以及（iv）生物工程（通过开发受喙启发的组织液探针）。这些基本原理可以应用于未来各种设备的设计，例如需要小体积流体检索和分析以及受控操作的应用，例如环境监测、生物医学和法医探测。

EFRI-BSBA: Lepidoptera proboscises as prototypes of multifunctional fluidic devices with distributed actuation and sensingPI Name: Konstantin KornevInstitution: Clemson UniversityProposal No. 0937985 Abstract Butterflies and moths, constituting the order Lepidoptera, have inspired decades of engineering research in aerodynamics, optics, and navigation. This project focuses on the lepidopteran proboscis, which is poorly explored from an engineering perspective. The goal is to develop fundamental principles of fiber-based microfluidics inspired by the lepidopteran fluidic system, and apply these principles to the design, fabrication, and manipulation of a new class of fiber-based devices capable of transporting and probing a previously impossible range of liquids. These principles will be validated using biological data from Lepidoptera. Through collaboration of engineers, chemists, and biologists, bioinspired proboscises will be fabricated by taking advantage of modern fiber technology, which offers fiber multifunctionality such as mechanical/electromagnetic memory, improved absorbency, and controlled wettability. A biomimetic approach will be developed for actuation, sensing, and control of the synthetic proboscis. The advantages will be illustrated for an artificial proboscis to probe fluids from individual vascular smooth muscle cells. The lepidopteran fluidic system is envisioned as shifting the current microfluidic paradigm from stationary channel-like structures to fiber-based microfluidic devices, providing distributed actuation, sensing, and manipulation with minute amounts of fluids. The project will serve as a catalyst for development of novel science, engineering, and technology at the interface of biology, chemistry, materials science, and mechanical, electrical, and bioengineering. The basic principles, identified by a multidisciplinary group, will impact multiple fields, including (i) integrative biology by providing insight into the physical function of the lepidopteran fluidic system, (ii) materials science by offering new knowledge on fluid-fiber interactions and relevant fiber design parameters, (iii) robotics and control by developing biomimetic methods for shape and fluid control, and (iv) bioengineering by developing proboscis-inspired tissue-fluid probes. The basic principles can be applied to the design of a wide range of future devices, as in applications requiring low-volume fluid retrieval and analysis coupled with controlled manipulation, such as environmental monitoring and biomedical and forensic probing.