Charge Transfer Processes at Electrochemical Nanointerfaces

在这个由化学部化学结构、动力学和机制项目支持的项目中，纽约城市大学皇后学院的Michael Mirkin教授和他的研究团队将利用Mirkin实验室开发的纳米电极和纳米管技术来探索薄层细胞和两种不混溶液体界面上的电荷转移动力学。这些研究集中在系统尺寸小于或与双电层厚度相当的情况下的界面电荷转移。一个很大程度上未开发的界面动力学领域。该研究项目还将涉及基于纳米电极的方法的发展，用于表征活细胞内产生的活性氧和活性氮物种。上述项目将与美国和国际科学家（匹兹堡大学Shigeru Amemiya教授和法国高等师范学院Christian Amatore教授）合作完成。拟议的研究与化学领域以外的科学和工程的各个领域直接相关。从纳米科学和分子电子学到替代能源系统和生命科学。活化巨噬细胞中活性氧和活性氮种类的研究可以促进免疫学的进步，有助于预防/治疗与氧化应激相关的代谢疾病。参与本项目的研究生和博士后将获得界面电化学、生物分析化学和纳米科学等多学科的研究经验。他们将受益于广泛的国家和国际合作。这项研究的结果将通过出版物和专业报告广泛传播。所要求的资金将使PI能够为纽约市立大学招募代表性不足的少数族裔STEM学生并参与其多样性倡议做出贡献。

In this project supported by the Chemical Structure, Dynamics and Mechanisms Program of the Chemistry Division, Professor Michael Mirkin and his research team at the City University of New York, Queens College will utilize nanoelectrode and nanopipet technologies developed in the Mirkin laboratory to explore the dynamics of charge transfers in thin layer cells and at the interface of two immiscible liquids. These studies are focused on interfacial charge transfer in situations where the system dimensions are smaller than or comparable to the thickness of the electrical double layer?a largely unexplored area of dynamics at interfaces. The research project will also involve the development of nanoelectrode based methods for the characterization of reactive oxygen and nitrogen species generated within living cells. The aforementioned projects will be done in collaboration with US and international scientists (Prof. Shigeru Amemiya at the University of Pittsburgh and Prof. Christian Amatore at the Ecole Normale Superieure, France). The proposed research is directly relevant to various areas of science and engineering beyond the field of chemistry?from nanoscience and molecular electronics to alternative energy systems and life sciences. The studies of reactive oxygen and nitrogen species in activated macrophages can lead to advances in immunology and contribute to the prevention/treatment of metabolic diseases related to oxidative stress. The graduate students and postdoctoral fellows involved in this project will get multidisciplinary research experience in interfacial electrochemistry, bioanalytical chemistry and nanoscience. They will benefit from extensive national and international collaborations. The results of this research will be broadly disseminated through publications and professional presentations. The requested funds with enable the PI to contribute to ongoing CUNY efforts to recruit underrepresented minority STEM students and participate in its diversity initiatives.