2010 Meiosis Gordon Research Conference and Gordon Research Seminar 2010

主持：Abby Dernburg副主持：Nancy hollingsworth减数分裂是一个特殊的细胞分裂过程，对有性生殖至关重要。在减数分裂过程中，“二倍体”细胞（每条染色体都有两个拷贝，分别来自亲本）分裂成“单倍体”细胞，如精子、卵子或花粉，每条染色体只包含一个拷贝。当这些单倍体细胞中的两个在受精时融合形成一个新的受精卵时，这导致二倍体染色体数量的恢复。在减数分裂期间，染色体进行遗传交换，也称为交叉重组，产生新的基因组合。这种重组过程既是个体物种遗传多样性的基础，也是新物种进化的基础。减数分裂的缺陷会导致不育，或者后代有一系列毁灭性的缺陷。2010年减数分裂戈登会议将汇集研究人员在各种各样的生物减数分裂。会议将集中讨论未发表的前沿研究，这些研究将由邀请的演讲者介绍，他们采用了多种方法，代表了广泛的观点。演讲者中将包括早期职业调查者，他们将有机会向专家观众展示他们的工作并获得反馈。今年会议的一个显著特点是增加了一个戈登-基南研究研讨会，这是一个在实际会议之前由学生和博士后组织的为期一天半的会议。研讨会为初级研究人员提供了一个见面的机会，并在随后的四天半会议中介绍了更深入的主题。研讨会和会议的目标都是提供一个高度互动的环境，以交流思想和发展合作，推动该领域向前发展。这一领域的进展将增强我们对细胞用来控制和协调复杂过程的基本机制的理解，这些过程如DNA修复和染色体分裂，对生命至关重要。

Chair: Abby Dernburg Vice-Chair: Nancy HollingsworthMeiosis is a specialized cell division process that is essential for sexual reproduction. During meiosis, a "diploid" cell, which contains two copies of each chromosome - one inherited from each parent - splits to form "haploid" cells such as sperm, eggs, or pollen, which contain only a single copy of each chromosome. When two of these haploid cells fuse at fertilization to form a new zygote, this results in restoration of the diploid chromosome number. During meiosis, chromosomes undergo genetic exchange, also known as crossover recombination, resulting in new combinations of genes. This recombination process underlies both genetic diversity within individual species and the evolution of new species. Defects in meiosis can give rise to infertility or to offspring with any of a wide range of devastating defects.The 2010 Meiosis Gordon Conference will bring together researchers studying meiosis in a broad variety of organisms. The meeting will focus on cutting-edge, unpublished research presented by invited speakers who employ a diverse array of approaches and who represent a wide range of perspectives. Included among the speakers will be early-career investigators who will have a chance to present their work to an expert audience for feedback. A notable feature of this year's gathering is the addition of a Gordon-Keenan Research Seminar, a 1½-day meeting preceding the actual conference and organized by students and postdoctoral fellows. The seminar offers an opportunity for junior researchers to meet each other and be introduced to the topics to be covered in more depth during the 4½-day conference immediately following. The goal of both the seminar and the conference is to offer a highly interactive environment for the exchange of ideas and development of collaborations that will move the field forward. Advances in this field will enhance our understanding of the fundamental mechanisms that cells use to control and coordinate complex processes - processes such as DNA repair and chromosome division - that are so essential to life.