Summer Undergraduate Research in Chemistry and Biochemistry at Miami University

该奖项由化学部（CHE）和生物基础设施部（DBI）颁发，支持由Christopher a . Makaroff在迈阿密大学（俄亥俄州）领导的本科生研究经验（REU）项目，从2010年开始为期三个夏天。该网站每年夏天将为10名学生提供为期10周的培训。研究项目侧重于化学和生物学跨学科领域的合作研究。样本项目包括：(1)最近发现的将完全折叠的蛋白质转运到类囊体腔的系统；(2)开发用于化学物质分离的聚合物色谱柱；(3)具有生物活性的天然产物的合成；(4)阐明体内条件下单宁的命运；(5)对光和/或化学刺激有反应的可重构表面的合成和研究；(6)蓝藻异囊分化的研究；(7)利用核磁共振方法研究整体膜蛋白的结构和动力学；(8)减数分裂和有丝分裂过程中参与染色体凝聚和姐妹染色单体内聚的蛋白质的研究；(9)设计和开发有效测量学生学习的工具。除了在研究活跃的机构接触前沿研究外，参加该计划的学生还将参加实地考察，专业发展活动和道德培训。计划招收的学生将来自那些没有重大研究机会的学校，以及那些化学专业学生人数不足的学校。作为培训的一部分，年轻科学家需要接触现代研究方法和工具。这个REU网站旨在为大量学生提供实用的，动手的研究培训，这些学生可能在他们的家庭机构没有这种机会。学生将在迈阿密大学（俄亥俄州）从事的跨学科项目是跨学科工作的优秀范例，这种跨学科工作越来越成为现代实验室研究最富有成果的典型途径。在这里参与研究的学生将为读研做好充分准备，并最终成为国家技术劳动力的一部分。

This award from the Division of Chemistry (CHE) and the Division of Biological Infrastructure (DBI) supports a Research Experience for Undergraduates (REU) site led by Christopher A. Makaroff at Miami University (Ohio) for three summers, commencing in 2010. The site will support ten students per summer in a ten week program. The research projects focus on collaborative research in interdisciplinary areas of chemistry and biology. Sample projects include: (1) the recently-discovered system that transports fully-folded proteins into the thylakoid lumen; (2) the development of polymeric columns for separations of chemical species; (3) the synthesis of biologically-active natural products; (4) the elucidation of the fate of tannin under in vivo conditions; (5) the synthesis and study of reconfigurable surfaces, responsive to light and/or chemical stimuli; (6) the study of heterocyst differentiation in cyanobacteria; (7) the study of the structure and dynamics of integral membrane proteins with NMR methods; (8) the study of proteins involved in chromosome condensation and sister chromatid cohesion during meiosis and mitosis; (9) the design and development of tools to effectively measure student learning . Besides being exposed to cutting-edge research at a research-active institution, the students participating in this program will participate in site visits, professional development activities, and ethical training. Students targeted for the recruitment to the proposed site will come from schools without significant opportunities for research as well as schools with large populations of students underrepresented in chemistry.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide practical, hands-on research training to a significant number of students who might not have this opportunity at their home institution. The interdisciplinary projects that the students will work on while at Miami University (Ohio) are excellent examples of the kinds of cross-disciplinary work that is becoming more and more typical of the most fruitful avenues for modern laboratory research. Students participating in research at this site will be well-prepared for graduate school, and eventual employment as part of the country's technical workforce.