EAGER: Applications of Molecular Encapsulation to Materials and Information Science

本研究计划的目标是扩展分子胶囊，以解决物理有机化学中的基本问题，并开发新的超分子材料。该提案的具体目标是：a)制备和表征新的多组分氢键组件；B)理解自组装和混合装配过程的动力学；c)探索这些组件作为分子器件、输送系统、有机催化剂和智能材料的使用。在大分子、超分子和纳米化学项目的支持下，斯克里普斯研究所斯卡格斯化学生物学研究所的朱利叶斯·雷贝克教授正在探索完全包围其他分子的分子的合成和性质。这种排列代表了化学中物质的独特相，并导致具有潜在广泛技术应用的材料。这个项目为学生的基础研究提供了一个很好的训练基地，因为它使他们接触到有机合成、化合物表征、光谱学以及手性、数据存储和纳米技术等方面的广泛经验。该项目将对社会产生重要影响，因为它将允许首席研究员主持，指导和培养有才华的高中教师，并为未来的高中生和教师实习制定研究计划。这些实习为培养国家未来的化学教授提供了早期的步骤。

This research program targets extended molecular capsules to address fundamental questions in physical organic chemistry and to develop novel supramolecular materials. Specific goals of the proposal are: a) preparing and characterizing new multicomponent hydrogen bonded assemblies; b) understanding the dynamics of self- and hybrid assembly processes; and c) exploring the use of these assemblies as molecular devices, delivery systems, organocatalysts and smart materials. With the support of this EAGER award from the Macromolecular, Supramolecular, and Nanochemistry Program, Professor Julius Rebek, of the Skaggs Institute for Chemical Biology at The Scripps Research Institute is exploring the synthesis and properties of molecules that completely surround other molecules. Such arrangements represent unique phases of matter in chemistry and lead to materials with potentially broad technological applications. This project serves as an excellent training ground for students in fundamental research because it exposes them to broad experiences in organic synthesis, compound characterization, spectroscopy, as well as issues in chirality, data storage and nanotechnology. This project will have an important impact on society because it will permit the Principal investigator to host, mentor and cultivate talented high school teachers and devise research plans for future high school student and teacher internships. These internships provide the early steps in the education of the nations future professors of chemistry.