MRI: Acquisition of an EPR spectrometer for studies in biochemistry, chemistry, and physics

有了这项重大研究仪器计划的奖励，来自马歇尔大学的Derrick Kolling教授和他的同事Michael Norton、Michael Castellani、Xiaoping Sun和Nalini Santanam将获得一台电子顺磁共振（EPR）光谱仪，该光谱仪具有液氮和液氦冷却系统，能够分析3.8 K至室温的气相、液相或固相样品。该提案旨在加强各级的研究培训和教育，特别是在以下领域：（a）离子电荷转移磁体的合成和定性;（B）通过超快冷冻淬灭装置捕获的瞬时催化状态;（c）使用光诱导ESP（LESR）来定性DNA折纸试验台中的分子线和多分子组装;（d）铀酰UO 2（2+）的化学和光化学还原;（e）稀磁半导体的研究;（f）心血管疾病中的氧化脂质。EPR分光计提供分子和固态材料的几何和电子结构的详细信息。它也可用于获得有关自由基寿命的信息，这些自由基是参与有价值的化学转化以及病理性肿瘤生长起始的短寿命、高反应性物种。这些研究将影响许多领域，从无机和有机分子的合成到新固态材料的开发，再到磁性和生物学意义的化合物。从正在进行的研究中得到启发的例子，这一工具将成为马歇尔大学以及查尔斯顿大学本科和研究生阶段研究和教学的一个组成部分。

With this award from the Major Research Instrumentation Program, Professor Derrick Kolling from Marshall University and colleagues Michael Norton, Michael Castellani, Xiaoping Sun and Nalini Santanam will acquire an electron paramagnetic resonance (EPR) spectrometer with liquid nitrogen and liquid helium cooling systems and the capability of analyzing samples in the gas, liquid, or solid phases from 3.8 K up to room temperature. The proposal is aimed at enhancing research training and education at all levels, especially in areas such as (a) synthesis and characterization of ionic charge-transfer magnets; (b) transient catalytic states trapped via an ultrafast freeze-quench apparatus; (c) using light-induced ESP (LESR) to characterize molecular wires and multimolecular assemblies in a DNA origami testbed; (d) chemical and photochemical reduction of uranyl UO2(2+); (e) study in diluted magnetic semiconductor; and (f) oxidized lipids in cardiovascular disease.An EPR spectrometer yields detailed information on the geometric and electronic structure of molecular and solid state materials. It may also be used to obtain information about the lifetimes of free radicals, short-lived, highly reactive species involved in valuable chemical transformations as well as the initiation of pathological tumor growth. These studies will impact a number of areas, from the synthesis of inorganic and organic molecules to the development of new solid state materials to compounds of magnetic and biological interest. Employing examples inspired from ongoing research, this instrument will be an integral part of research and teaching at the undergraduate and graduate levels at Marshall University as well as at the University of Charleston.