I-Corps: Roadmap to Commercialization for Electric Field Encephalography

I-Corps团队正在开发一种用于大脑信号监测的电场测量技术。这项技术是一种测量和分析大脑内部活动或外部刺激产生的电场的系统。它由高密度的传感器阵列系统组成，伴随着电子和信号处理算法。与目前的方法、脑电图（测量头皮上的电位）和脑磁图（测量磁场）相比，这种技术有几个优点。该技术具有较高的空间分辨率，不受杂散磁场的影响，不需要低温设备，提高了源重构精度。通过该项目开发的技术有可能为理解大脑活动和获得各种神经系统疾病的线索提供新的信息。通过该项目开发的技术是一种新的脑信号测量系统，适用于研究人员和临床医生，它将具有成本效益和完全便携式/移动。以高空间分辨率和用户友好的方式测量生物电大脑信号的能力可能会导致新的民用和军事应用。这项技术的一些直接影响领域可能包括：高时间和空间分辨率的功能性脑成像、模式识别、认知；对视觉和语言的神经关联的认识；再次，睡眠、癫痫和精神健康的研究和应用；创伤性脑损伤的军事应用，作战人员的性能评估和提高；人机和脑机接口。

The I-Corps team is developing an electric field measurement technology for brain signal monitoring. This technology is a system of measuring and analyzing the electric fields generated by the brain arising from intrinsic activity or external stimuli. It is comprised of a system of high density array of sensors, accompanied by electronics and signal processing algorithms. This technique used through this technology has several advantages over current modalities, Electroencephalography (measuring the electric potential on the scalp) and Magneto-encephalography (measuring the magnetic field). This technology has higher spatial resolution, is unaffected by stray magnetic fields, does not cryogenic equipment and improves source reconstruction precision. Technologies developed through this project have the potential to provide new information for understanding brain activity and obtaining clues to a variety of neurological disorders.The technology developed through this project is a new brain signal measurement system for researchers and clinicians, which would be cost-effective and fully portable/mobile. The ability to measure bioelectric brain signals at high spatial resolution and in a user-friendly manner may lead to new civilian and military applications. Some of the immediate areas of impact of this technology could include: Functional brain imaging at high temporal and spatial resolution, pattern recognition, cognition; insights into neural correlates of vision and speech; again, sleep, epilepsy and mental health research and applications; military applications of traumatic brain injury, war-fighter performance assessment and enhancement and; human-machine and brain-computer interfaces.