Genome wide screening for gene products that regulate the celluar dynamics of lipid droplets

肥胖是一种流行病，如果不加以制止，将导致澳大利亚出现巨大的社会和经济问题。从本质上讲，人类肥胖的标志是细胞脂滴的积累。这项研究将通过提供对脂滴如何形成的基本理解而使澳大利亚受益。这将在科学层面产生直接的国际影响，也将为治疗肥胖提供新的目标和策略。这项拟议中的研究还将为提高植物种子的石油产量提供策略，从而使澳大利亚农业受益。

Obesity is a pandemic that if not stopped, will lead to huge social and economic problems in Australia. In essence, the hallmark of human obesity is the accumulation of cellular lipid droplets. This research will benefit Australia by providing a fundamental understanding of how lipid droplets are formed. This will have immediate international impact at the scientific level and will also provide novel targets and strategies for treating obesity. The proposed study will also benefit Australian agriculture by providing strategies to improve oil production from plant seeds.