MRI: Acquisition of a 400 MHz NMR Spectrometer to Support Research and Undergraduate Research Training at Carleton College and St. Olaf College

在主要研究仪器项目（MRI）的资助和化学研究仪器项目（CRIF）的支持下，卡尔顿学院的Gretchen Hofmeister教授及其同事David Alberg和Matthew white将获得一台400 MHz的核磁共振光谱仪，该光谱仪具有场梯度能力，可用于二维和动态核磁共振实验。该光谱仪将允许在各种领域进行研究，例如那些加速具有重要经济意义的化学反应的领域，以及允许对生物学相关物种进行研究。总的来说，核磁共振（NMR）波谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对合成有机/无机化学、材料化学和生物化学产生影响。该仪器将成为卡尔顿学院和圣奥拉夫学院本科生教学和研究的一个组成部分。该奖项旨在加强各级的研究和教育，特别是在以下领域：(a)锥虫硫酮还原酶抑制剂的研究；(b)扩展线性链（ELC）材料的合成与应用；(c)三酚酸钛催化剂的研究；(d) organocatalysis;(e)金属/配体协同反应性研究；(f) Mo（II）乙酰基配合物的合成和结构。

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor Gretchen Hofmeister from Carleton College and colleagues David Alberg and Matthew Whited will acquire a 400 MHz NMR spectrometer with field gradient capabilities for two-dimensional and dynamic NMR experiments. This spectrometer will allow research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as allow study of biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research performed by undergraduate students at Carleton College and St. Olaf College. The award is aimed at enhancing research and education at all levels, especially in areas such as (a) studies of trypanothione reductase inhibitors; (b) synthesis and applications of extended linear chain (ELC) materials; (c) studies of titanium(IV) trisphenolate catalysts; (d) organocatalysis; (e) studies of metal/ligand cooperative reactivity; and (f) synthesis and structure of Mo(II) acetyl complexes.