UNS: Design and Synthesis of Particles for Opto-magnetic Trapping

CBET -1507758 PI：克拉克，罗伯特科学家和工程师有几种方法可以在微米尺度上操纵粒子及其环境。 两种这样的方法，光学捕获和磁捕获，提供了可以使用外部场来操纵粒子而无需直接进入系统的优点。 这两种技术可以结合起来，以改善粒子的操纵，但很少有粒子具有所需的属性，以响应光学和磁捕获。 本项目将开发具有适当材料性质的定向磁性微粒，使其具有光学和磁性联合操纵的上级性质。本项目提出了一种先进的制造技术，用于生产能够同时进行光学和磁性捕获和操纵的新型超顺磁性微粒。这些粒子是通过磁性纳米粒子在光学非线性流体介质中的定向自组装产生的。然后将光学非线性介质暴露于成形的超快激光源，由于多光子吸收相变而导致颗粒的形成。新粒子的磁性将远远超过现有技术粒子的磁性，并且将在涉及分子光谱学和智能结构的先进制造（例如基于自适应液晶的成像系统）的生物技术应用中具有影响力和潜在的变革性。

CBET - 1507758PI: Clark, RobertScientists and engineers have available several methods to manipulate particles and their environments at the micron scale. Two such methods, optical trapping and magnetic trapping, offer the advantage that particles can be manipulated using external fields without direct access to the system. These two techniques can be combined to improve particle manipulation, but few particles have the required properties to respond to both optical and magnetic trapping. This project will develop oriented magnetic micro-particles with appropriate arrangements of material properties to give the particles superior properties for combined optical and magnetic manipulation.This project presents an advanced manufacturing technique for producing a novel type of super-paramagnetic microparticle capable of simultaneous optical and magnetic trapping and manipulation. These particles are produced via the directed self-assembly of magnetic nano-particles within an optically nonlinear fluid media. The optically nonlinear media is then exposed to a shaped ultrafast laser source causing the formation of particles due to multiphoton absorption phase change. The magnetic properties of the new particles will far exceed those of current state of the art particles and will be influential and potentially transformative in biotechnology applications involving molecular spectroscopy and advanced manufacturing of smart structures such as adaptive liquid crystal-based imaging systems.